Adenocarcinoma of the esophagus has increased dramatically within the United States and continues to have a poor prognosis despite aggressive treatment. Identifying potential risk factors is critical for the early detection and treatment of this disease. The present case report describes a very young woman who developed adenocarcinoma of the esophagus after only a brief history of bulimia. Thes...

9 Goldman MC, Beckman RC: Barrett syndrome: Case report with discussion about concepts of pathogenesis. Gastroenterology 39: 104-1 10, 1960 10 Som ML, Wolf BS: Peptic ulcer of the esophagus and esophagitis in gastric lined esophagus. JAMA 162:641644. 1956 11 Adler RH: The lower esophagus lined by columnar epithelium. Its association with hiatal hernia, ulcer, stricture and tumor. J Thor Cardiov...

Background: Prenatal esophageal atresia (EA) diagnosis may improve outcomes by optimizing prenatal and postnatal care. This study evaluated the feasibility of direct antenatal visualization normal longitudinal sections using two-dimensional ultrasound between 21 23 gestational weeks. Methods: A detailed anatomic survey was performed, followed dedicated imaging. The latter performed as follows: ...

The paper presents a clinical case of successful treatment for fourth-grade achalasia cardia using video laparoscopic esophagocardiomyotomy with esophagocardiogastroplasty according to T.A. Suvorova. surgery involves peculiar process – the triangular-folded anterior wall stomach is sutured edges formed defect in muscular layer esophagus and cardia. In early late postoperative period, patients d...

The objective of this study was to examine the associations between dietary patterns and the risk of Barrett's esophagus, a precursor to esophageal adenocarcinoma. The authors conducted a case-control study within the Kaiser Permanente Northern California population between 2002 and 2005. Patients with a new diagnosis of Barrett's esophagus (n = 296 cases) were matched to persons with gastroeso...

Barrett's esophagus is a condition in which the normal stratified squamous epithelium of the distal esophagus is replaced by intestinal metaplasia. For more than three decades, the prevailing clinical paradigm has been that Barrett's esophagus is a complication of symptomatic reflux disease that predisposes to esophageal adenocarcinoma. However, no clinical strategy for cancer prevention or ear...

Barrett's esophagus is a useful model for the study of carcinogenesis, as the metaplastic columnar epithelium that replaces squamous esophageal epithelium is at elevated risk for development of adenocarcinoma. We examined telomere length and chromosomal instability (CIN) in Barrett's esophagus biopsies using fluorescence in situ hybridization. To study CIN, we selected centromere and locus-spec...

AIM To compare expression of Ca(2+)-regulating proteins in upper gastrointestinal (GI) tract of achalasia patients and healthy volunteers and to elucidate their role in achalasia. METHODS Sarcoplasmic reticulum Ca(2+) ATPase (SERCA) isoforms 2a and 2b, phospholamban (PLB), calsequestrin (CSQ), and calreticulin (CRT) were assessed by quantitative Western blotting in esophagus and heart of rats...

Barrett’s esophagus is a condition in which the normal stratified squamous epithelium of the distal esophagus is replaced by intestinal metaplasia. For more than three decades, the prevailing clinical paradigm has been that Barrett’s esophagus is a complication of symptomatic reflux disease that predisposes to esophageal adenocarcinoma. However, no clinical strategy for cancer prevention or ear...