introduction and aims: the role of human papillomavirus (hpv) in the etiology of esophageal squamous cell carcinoma (escc) is not clear. previous studies have found highly variable (from 0% to 67%) prevalence of hpv in escc tumor. however, prevalence of hpv in escc tumor seems to be higher in areas with high incidence of escc , such as china and south africa. iran is one of the areas of the wor...

objective(s):  cd44 is a member of the cell adhesion molecules family. naturally, cd44s, along with cd44v3 influence the cell motility, migration, and adhesion, while in tumor cells they lead to tumor invasion, progression, and metastasis. the purpose of this research is to evaluate the cd44s and cd44v3 expression in esophageal squamous cell carcinoma (escc) and to reveal their correlations wit...

The incidence of esophageal squamous cell carcinoma (ESCC) is very high in northern China. This cancer has a very poor prognosis, mostly because it is usually diagnosed at a late stage. Detection at an earlier stage can dramatically improve prognosis. Microscopic evaluation of esophageal balloon cytology (EBC) specimens has been the most common method for early detection of ESCC, but this techn...

A 74-year-old woman was admitted to our unit with complaints of abdominal discomfort and heartburn over 2 months. She had a history of hypertension and celiac disease, but admitted that she did not comply with a gluten-free diet. She had no history of any medication, smoking, or drinking alcohol, and her family history was unremarkable. Physical examination findings were normal. Serological stu...

in this archival analysis of genetic & protein alterations in the p53 tumor suppressor gene, we used immunohistochemical methods for detection of these alterations. the tumor series includes: 61 paraffin embedded esophageal squamous cell carcinoma from a high incidence (ethnic) & a non-high incidence regions in iran.

HEADINGS Esophageal neoplasms. Neoplasms, squamous cell. Adenocarcinoma. Esophagectomy. ABSTRACT Background Medical literature has recorded a significant and progressive increase in the prevalence of esophageal adenocarcinoma in recent years, and this fact has epidemiological importance in the treatment, in the evolution and prognosis of patients. Aim A retrospective study of esophageal tumors ...

Cyclo-oxygenase (COX)-2 is not usually detectable in normal tissues but is induced in inflammation and carcinogenesis. The level of COX-2 is elevated in cancer tissues of the colon, bladder, and skin. In the esophagus, squamous cell carcinoma and adenocarcinoma are known to express COX-2. The purpose of this study was to clarify the association of COX-2 expression with clinicopathological facto...

Tracheal penetration of esophageal self-expanding metallic stents (SEMS) with/without tracheoesophageal fistula (TEF) formation is a rare occurrence. We report the case of a 66-year-old female patient with advanced esophageal squamous cell carcinoma who had undergone palliative esophageal stenting on three occasions for recurrent esophageal stent obstruction. On evaluation of symptoms of breath...

Basaloid squamous cell carcinoma of the esophagus is very rare. Further, polypoid type of esophageal cancer is also rare. We have recently treated a case of basaloid squamous cell carcinoma which presented as a 1.3-cm esophageal polyp. A 48-year-old woman was referred to our hospital because of a polypoid mass at 36 cm distance from the upper incisor on endoscopic examination, and the result of...