Ochronosis or black joints disorder is a rare autosomal recessive disorder caused by deficiency of homogentisic acidoxidase. Orthopaedic manifestations are common and mostly involve spine and large joints such as knee and hip.Arthropathy is progressive and will eventually leads to arthroplasty. Not being familiar with this disorder might lead todevastating complications. We present a 57 year-ol...

BACKGROUND Sleeve gastrectomy may alter esophageal motility and lower esophageal sphincter pressure. AIM To detect manometric changings in the esophagus and lower esophageal sphincter before and after sleeve gastrectomy in order to select patients who could develop postoperative esophageal motilitity disorders and lower esophageal sphincter pressure modifications. METHODS Seventy-three pati...

BACKGROUND Previous investigations on risk factors for orthotopic liver transplantation (OLT) surgery have not analyzed hemodynamic aberrations in great detail. Moreover, the usefulness of esophageal Doppler monitoring has not been extensively studied in this clinical setting. The aim of this study was to evaluate if the occurrence of primary graft dysfunction (PGD) may be anticipated by hemody...

The Foker process is a method of esophageal lengthening through axial tension-induced growth, allowing for subsequent primary reconstruction of the esophagus in esophageal atresia (EA). In this unique case, the Foker process was used to grow the remaining esophageal segment long enough to attain esophageal continuity following failed colonic interpositions for long-gap esophageal atresia (LGEA)...

Benign esophagorespiratory fistula is a rare but often lethal affection and difficult to cure. Possible treatments are surgery or esophageal stenting but may fail and cause respiratory failure. Two patients with spontaneous esophagorespiratory fistula after chemoradiotherapy for an esophageal malignancy were both treated by esophageal exclusion but esophageal stent were left in place. The esoph...

OBJECTIVE To report the incidence of congenital vascular anomalies in a cohort of patients with esophageal atresia (EA) and tracheoesophageal fistula (TEF) while describing the clinical presentation, diagnosis, and consequences, and to evaluate the diagnostic value of esophagram in diagnosing an aberrant right subclavian artery (ARSA). METHODS All patients born with EA/TEF between 2005 and 20...

We recently witnessed a neonatal intensive care unit infant succumb to tracheal agenesis and noticed, at the same time, in the news headlines of adults being “saved” by “labmade tracheas” [1]. This stimulated our curiosity to review recent developments in tissue engineering and stem cell research that may challenge prior authors' claims that tracheal agenesis is “uniformly fatal” [2]. Although ...

BACKGROUND The distal esophagus harbors a complex bacterial population. We hypothesized that a better understanding of bacterial communities in the esophagus would facilitate understanding of the role of bacteria in esophageal disease. Here, we investigated bacterial composition in the distal esophagus in subjects with a normal esophagus, reflux esophagitis, and Barrett's esophagus. METHODS T...

BACKGROUND There are conflicting data concerning the effect of gastroesophageal reflux disease (GERD) on esophageal motor function. HYPOTHESIS Duration of GERD might affect severity of symptoms, grade of esophageal mucosal injury, and esophageal motor behavior. DESIGN Retrospective study of a defined cohort. SETTINGS Two referral centers, one of them academic, for esophageal gastrointesti...