Colorectal cancer is the third most common cancer among both men and women in the United States and the second leading cause of cancer death. Endoscopic submucosal dissection (ESD) is an innovative advanced endoscopic therapy for superficial gastrointestinal neoplasms which is rapidly becoming standard of care particularly in Asia. ESD was first developed for the resection of early gastric canc...

As device dimensions scale down and the operating speed of integrated circuits scales up, electrostatic discharge (ESD) proves an increasingly more critical issue. With hundreds of gigahertz I/O pads in typical data communication circuits, microprocessors, and memories, both the voltage tolerance and the area of ESD protection devices become important design parameters. It is possible to use in...

SUMMARY An impedance-isolation technique is proposed for on-chip ESD protection design for radio-frequency (RF) integrated circuits (ICs), which has been successfully verified in a 0.25-μm CMOS process with thick top-layer metal. With the resonance of LC-tank at the operating frequency of the RF circuit, the impedance (especially, the parasitic ca-pacitance) of the ESD protection devices can be...

Background and Aims. Conventional endoscopic submucosal resection (EMR) of carcinoid tumors often involves the resection margin, which necessitates further intervention. Endoscopic submucosal dissection (ESD) is widely accepted for removing carcinoid tumors. We aimed to evaluate the clinical usefulness of ESD with that of EMR for resection of type I gastric carcinoid tumors. Patients and Method...

Aim. Delayed bleeding after endoscopic submucosal dissection (ESD) for gastric epithelial neoplasms is a major complication. We investigated factors related to post-ESD bleeding to identify preventive measures. Methods. The study included 161 gastric epithelial neoplasms in 142 patients from June 2007 to September 2010. Post-ESD bleeding was defined as an ulcer with active bleeding or apparent ...

BACKGROUND AND STUDY AIMS  Few studies have directly compared endo-knives for endoscopic submucosal dissection (ESD) in humans. We compared the performances of the Mucosectom2 and SB knife Jr. PATIENTS AND METHODS  Two trainee endoscopists performed ESD of 36 lesions in this prospective, randomized controlled trial. Mucosal incision with a 1.5-mm Dual knife and submucosal dissection using the...

When successive stages in the life history of an animal directly overlap, physiological conflicts can arise resulting in carryover effects from one stage to another. The extreme egg-size dimorphism (ESD) of Eudyptes penguins, where the first-laid A-egg is approximately 18-57% smaller than the second-laid B-egg, has interested researchers for decades. Recent studies have linked variation in this...

BACKGROUND/AIMS Surgeons must be aware of risk factors for strictures before performing endoscopic submucosal dissection (ESD), to enable early interventions to prevent severe strictures. METHODS This study was a single-center retrospective study. We reviewed the clinical data of patients who has undergone gastric ESD from January 2007 to December 2012. RESULTS Among the 3,819 patients who ...

PURPOSE To compare medical costs of endoscopic submucosal dissection (ESD) and transanal endoscopic microsurgery (TEM) for the treatment of rectal tumors. METHODS The records of 80 patients who underwent ESD and 32 who underwent TEM for the treatment of rectal tumors were collected. Factors compared in the two groups included patient age, sex and clinical characteristics, as well as hospital ...

BACKGROUND AND STUDY AIMS Endoscopic submucosal dissection (ESD) is widely used in the resection of gastric tumors en bloc, however, complications such as pyrexia frequently occur following the procedure. The study aim was to elucidate the incidence, clinical characteristics, and risk factors of post-ESD pyrexia. PATIENTS AND METHODS We conducted a retrospective cohort study of 471 consecutiv...