BACKGROUND Emergence of extended-spectrum beta-lactamases (ESBLs) in Shigella species imparting resistance to third-generation cephalosporins is a growing concern worldwide. The aim of this study is to molecularly characterize the newly emerging beta-lactam resistant Shigella sonnei, specifically ESBLs in Lebanon, and compare them to beta-lactam sensitive isolates. METHODOLOGY We compared fiv...

BACKGROUND: Meropenem is a member of the antibiotic class of carbapenems, which are broad-spectrum antibiotics that possess activity against several drug-resistant organisms. Notably, the carbapenems maintain activity against extended-spectrum beta-lactamase (ESBL)-producing organisms. Additionally, the spectrum of activity of the carbapenems, excluding ertapenem, includes Pseudomonas aeruginos...

Background: Escherichia coli are ubiquitous bacteria colonising both humans and animals. Extended spectrum β-lactamase-producing E. has been selected as a suitable indicator for the monitoring surveillance of antimicrobial resistance. Death due to resistant is continuously rising in Cameroon, but contribution aviary sector not well studied. Therefore, this study aimed investigate resistance pro...

objective(s) the aim of this study was to investigate the presence of per-1-type esbls in drug resistant pseudomonas aeruginosa isolates. materials and methods during one-year period (2008-2009), following isolation and identification of 56 p. aeruginosa, the e-test method was performed for determination of minimal inhibitory concentration of ceftazidim. the isolates that they had mic≥16 µg/ml ...

We studied the prevalence of ceftazidime resistance in Pseudomonas aeruginosa and the rates of extended-spectrum β-lactamase (ESBL), AmpC β-lactamase (AmpC) and metallo-β-lactamase (MBL) production among the ceftazidime resistant Pseudomonas aeruginosa. A very high rate of MBL production was observed, which suggested it to be an important contributing factor for ceftazidime resistance among Pse...

b ackground: in recent decades, extended spectrum beta-lactamase (esbl) producing bacteria have increased worldwide. the most important causative agents of nosocomial infections throughout the world, escherichia coli and klebsiella pneumoniae as main esbl-producing bacteria are so highly regarded. trends  in  the  treatment  of  infections  by such  bacteria  have  led  to  a  global concern. t...

BACKGROUND & AIM The aim of this study was the detection of OqxAB efflux pumps, OmpK35 and OmpK36 porins among extended-spectrum-β-lactamase-producing Klebsiella pneumoniae isolates from Iran. MATERIALS AND METHODS This study was conducted with 83 K. pneumoniae isolates from two hospitals in Tehran, Iran. Antibiotic susceptibility tests were performed by Kirby-Bauer disc diffusion and Broth M...

Background: Higher prevalence of ESBL producers is alarming in dairy sector. So limiting antimicrobial use may curtail the selection and persistence predominant conjugative plasmids among strains. The study was aimed to determine occurrence extended-spectrum beta-lactamase (ESBL) producing E. coli as well their genetic diversity, resistance integrons bovines. Methods: A total 180 faecal samples...

Extended-spectrum ß-lactamases (ESBL) are a major source of concern. ESBL have been recorded around the world. Globally, number people infected with Enterobacteriaceae that produce extended-spectrum beta-lactamase is on rise. It has rise in resistance to ß-lactam antibiotics among them. In this study, objective was collect Escherichia coli isolates from Urinary tract infection patients using se...