PURPOSE To describe a case of severe dry eye syndrome in a child. METHODS Observational case report. The authors describe a 10-year-old male with severe dry eyes who was profoundly disabled by pain and photophobia despite aggressive conventional therapy. Lacrimal gland histology was consistent with the primary Sjögren syndrome, and serologic and immunohistologic evidence supported the hypothe...

OBJECTIVES Cytomegalovirus and Epstein-Barr virus remain leading causes of morbidity and mortality in the living-donor liver transplant population, particularly in pediatric patients. Herein we compare the incidence, timing, and risk factors for infection in this group. MATERIALS AND METHODS We performed a retrospective study of 344 consecutive pediatric patients 193 women (56.1%) who receive...

Most patients with seropositive rheumatoid arthritis, and a variable but lesser percentage of normal subjects, have precipitating antibodies to a nuclear antigen, rheumatoid arthritis nuclear antigen, present in Epstein-Barr virus-infected human B lymphoblastoid cells. We have used a sensitive indirect immunofluorescence assay for antibody to rheumatoid arthritis nuclear antigen in a study of p...

Several diseases are associated with Epstein-Barr virus (EBV) and they can be life-threatening, especially in immunocompromised individuals. Moreover, there no well-established EBV prevention control strategies Nigeria. Therefore, this study was carried out to assess the prevalence of (EBNA) IgM antibody among Public Health Workers Port-Harcourt, A cross-sectional survey adopted randomly analyz...

Recent studies have shown that the nonlinear jump-diffusion models give results which are in agreement with financial data. Here we provide linearization criteria together transformations linearize compound Poisson processes. Furthermore, introduce stochastic integrating factor to solve linear equations. Extended Cox–Ingersoll–Ross, Brennan–Schwartz and Epstein be linearizable their explicit so...

Gastric cancer (GC) is the fifth most common cancer in the world and accounts for 7% of the total cancer incidence. The prognosis of GC is dismal in Western countries due to late diagnosis: approximately 70% of the patients die within 5 years following initial diagnosis. Recently, integrative genomic analyses led to the proposal of a molecular classification of GC into four subtypes, i.e.,micro...

OBJECTIVES The aim of the present study was to assess the prevalence of Herpes Simplex virus, Epstein Barr virus and Human Papilloma virus -16 in oral lichen planus cases and to evaluate whether any clinical variant, histopathological or demographic feature correlates with these viruses. STUDY DESIGN The study was conducted on 65 cases. Viruses were detected immunohistochemically. We evaluate...

The two regions of the Epstein-Barr virus genome carrying partially homologous clusters of short tandem repeats (DSL and DSR [duplicated sequences, left and right, respectively] ) are transcribed into polyadenylated RNA upon spontaneous or chemical induction of the lytic virus cycle. In Raji, an Epstein-Barr virus genome carrying a nonproducer cell line, transcription of DSL and DSR is only obs...

INTRODUCTION Epstein-Barr virus esophagitis in an immunocompetent host is a rare entity. It represents either primary infection or reactivation and is usually characterized by acute onset and extensive ulcerative involvement of the upper and middle third of the esophagus. CASE PRESENTATION A case of Epstein-Barr virus esophagitis in a 27-year-old woman with no immunosuppressive factors, and h...

A simple gel technique is described for the detection of large, covalently closed, circular DNA molecules in eucaryotic cells. The procedure is based on the electrophoretic technique of Eckhardt (T. Eckhardt, Plasmid 1:584-588, 1978) for detecting bacterial plasmids and has been modified for the detection of circular and linear extrachromosomal herpesvirus genomes in mammalian cells. Gentle lys...