It is well-understood that wound care poses a significant burden on the healthcare system and patient well-being. As such, it imperative to develop efficient methods facilitate tissue repair. Our group previously developed nutritional gel scaffold, proven accelerate Due its gel-like properties, this scaffold requires time-consuming reconstitution, optimized for cavernous wounds. This pilot stud...

Background: Fungal keratitis is often difficult to eradicate and requires long treatment. Antifungal agents have lower efficacy because of low tissue penetration the indolent nature infection. Fluconazole has effective ocular ability, reaching aqueous concentration as same plasm concentration. Multilayer amniotic membrane transplantation (MLAMT) been shown be a promising surgical procedure reco...

Introduction: This article studies the wound healing activity of flavonoid schaftoside – apigenin -6-C-β-D glucopyranosyl 8-C-α-L arabinopyranoside (C26H28O14) isolated from above-ground part Lyсhnis chalcedonica L. Materials and Methods: The experiments were carried out on sexually mature mongrel male CD-1 mice. effect was studied a model plane skin wound. Schaftoside applied externally (topic...

Current skin substitutes fail to meet the need for replacement in full-thickness wounds. Bioprinting is a promising alternative method generate substitutes, as it can replicate structural organization of into biomimetic layers. In prior studies, we demonstrated that wounds treated with bioprinted had accelerated wound healing driven by epithelialization reduced contraction and immunofluorescent...

BACKGROUND Stress, both acute and chronic, can impair cutaneous wound repair, which has previously been mechanistically ascribed to stress-induced elevations of cortisol. Here we aimed to examine an alternate explanation that the stress-induced hormone epinephrine directly impairs keratinocyte motility and wound re-epithelialization. Burn wounds are examined as a prototype of a high-stress, hig...

Decellularized porcine kidneys were recellularized with renal epithelial cells by three methods: perfusion through the vasculature under high pressure, perfusion through the ureter under high pressure, or perfusion through the ureter under moderate vacuum. Histology, scanning electron microscopy, confocal microscopy, and magnetic resonance imaging were used to assess vasculature preservation an...