During surgical procedures, patients can have potentially life-threatening hypotension that requires immediate treatment with ephedrine sulfate, which compounding at the patient’s bedside. This study was conducted to validate and compare Nexus Pharmaceutical’s EMERPHED®, a pre-diluted sulfate injection, commercially used concentrated in simulated clinical setting. Twenty-four simulations were p...

Background: Spinal anaesthesia is widely used for caesarean surgery because it provides a fast and profoundsensory motor block, on the other hand Hypotension very common complication of spinal anaesthesia.Hence Ephedrine infusion has to be control hypotension.Method: Out 60 (sixty), 30 were administrated with ephedrine controlled group was samequantity normal saline during anaesthesias. Hemodyn...

The stereoselective synthesis of P-chirogenic diphosphinotriazoles using ephedrine methodology was described. coordination behavior these compounds as P,P-ligands has been demonstrated by the preparation well spectroscopic and X-ray crystallographic analyses a palladium complex. efficiency new diphosphines in palladium-catalyzed asymmetric allylic substitution reaction also evaluated.

5,6,7,8-Tetrahydro-1,3-dioxolo[4,5-g]isoquinoline (TDIQ) is a conformationally restricted phenylalkylamine related in structure to amphetamine and N-methyl-1-(3,4-methylenedioxyphenyl)-2-aminopropane (MDMA) that does not act as a locomotor stimulant. To further evaluate this agent, a group of six rats was trained to discriminate 5.0 mg/kg of TDIQ from vehicle and tests of stimulus generalizatio...

This paper explores possibilities of applying enantiomeric profiling to solving problems related to estimation of drugs usage in communities via the sewage epidemiology approach: for the identification of whether drug residue results from consumption of illicit drug or metabolism of other drugs, verification of potency of used drugs and monitoring of changing patterns of drugs abuse. Due to the...

BACKGROUND Spinal anesthesia is a standard technique for cesarean section but can cause hypotension which may be related to venous pooling secondary to progesterone-induced decreases in vascular tone. This study investigated the use of a sequential compression mechanical pump with thigh-high sleeves with compression cycles timed to venous refilling. We hypothesized that this would recruit poole...

This was a prospective randomized double blind controlled study to compare intubating conditions at 60 seconds with rocuronium 0.6 mg/kg by using three different induction techniques: propofol-placebo (PP), propofol-ephedrine (PE) and propofol-placebocrystalloid (PC). Ninety patients were included and randomly allocated to receive one of the three combinations. The patients were induced using f...