نتایج جستجو برای: enzymatic extraction

تعداد نتایج: 219125  

Journal: :Journal of the American Chemical Society 2017
Cynthia M Hong David M Kaphan Robert G Bergman Kenneth N Raymond F Dean Toste

This study offers a detailed mechanistic investigation of host-guest encapsulation behavior in a new enzyme-mimetic metal-ligand host and provides the first observation of a conformational selection mechanism (as opposed to induced fit) in a supramolecular system. The Ga4L4 host described features a C3-symmetric ligand motif with meta-substituted phenyl spacers, which enables the host to initia...

Journal: :Journal of molecular biology 2008
Jesse G Zalatan Timothy D Fenn Daniel Herschlag

Mechanistic models for biochemical systems are frequently proposed from structural data. Site-directed mutagenesis can be used to test the importance of proposed functional sites, but these data do not necessarily indicate how these sites contribute to function. In this study, we applied an alternative approach to the catalytic mechanism of alkaline phosphatase (AP), a widely studied prototypic...

2017
Kenneth R Beyerlein Dennis Dierksmeyer Valerio Mariani Manuela Kuhn Iosifina Sarrou Angelica Ottaviano Salah Awel Juraj Knoska Silje Fuglerud Olof Jönsson Stephan Stern Max O Wiedorn Oleksandr Yefanov Luigi Adriano Richard Bean Anja Burkhardt Pontus Fischer Michael Heymann Daniel A Horke Katharina E J Jungnickel Elena Kovaleva Olga Lorbeer Markus Metz Jan Meyer Andrew Morgan Kanupriya Pande Saravanan Panneerselvam Carolin Seuring Aleksandra Tolstikova Julia Lieske Steve Aplin Manfred Roessle Thomas A White Henry N Chapman Alke Meents Dominik Oberthuer

Unravelling the interaction of biological macromolecules with ligands and substrates at high spatial and temporal resolution remains a major challenge in structural biology. The development of serial crystallography methods at X-ray free-electron lasers and subsequently at synchrotron light sources allows new approaches to tackle this challenge. Here, a new polyimide tape drive designed for mix...

Journal: :Trends in biochemical sciences 2003
Arthur Kornberg

Reflections on advances and retreats in biochemistry have, over the years, generated several maxims. The late Efraim Racker’s ‘don’t waste clean thinking on dirty enzymes’ has been one of the most durable. On the occasion of a lecture in Jerusalem a decade ago, I framed a list of the ten ‘best’ maxims as ‘commandments’, which were later published as a ‘Guest Commentary’ in the Journal of Bacter...

ژورنال: Medical Laboratory Journal 2015
, , Fallah Mehrabadi, J, , Haddadi, A, , Mahboobi, R, , Mashhadi, R, , Pourmand, MR, ,

Abstract Background and Objective: Increased antibiotic resistant strains and inadequacy of current vaccines against pneumococcal infections necessitate the study of novel protein antigens. It seems that minor autolysin of Streptococcus pneumoniae may have antigenicity. Thus, we aimed at cloning its gene for the first time. Material and Methods: After DNA extraction of Streptococcus pneumoniae ...

Journal: :Fermentation 2022

To realize the utilization of valorization buckwheat waste (BW), a two-stage thermal-chemical process was explored and evaluated to produce saccharides biochar. During first stage, BW underwent hydrothermal extraction (HTE) varying severity explore feasibility production; then, sum yields in liquid sample were compared. A higher 4.10% obtained at relatively lower factor (SF) 3.24 with byproduct...

Journal: :Sustainability 2021

Pectin from sugar beet (Beta vulgaris L.) (SBP) was extracted a waste (SBW) registering 4.4% (w/w) yield. SBP presented weight-average molar mass of 459 kDa, galacturonic acid content 52.2%, and low esterification degree (30%). The macromolecular characteristics revealed flexible extended coil chain conformation. main neutral sugars in were galactose (20.7%), mannose (5.0%), arabinose (3.60%) w...

Journal: :Food and Bioproducts Processing 2021

The simultaneous extraction and enzymatic hydrolysis of sinapine from a mustard residue was designed for the recovery sinapic acid, high value-added phenolic acid. An initial screening allowed identification sinapoyl esterase activities in commercial cocktails (Depol 740 L, Ultraflo XL, Deltazym VR AC-100, Pectinase-PL “Amano”) mono-enzymatic solution rumen feruloyl esterase. These were not ver...

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