BACKGROUND Endometriosis is a benign and progressive disease with a high prevalence. Women with endometriosis, especially with atypical endometriosis, have a higher probability for developing ovarian cancer compared with women without endometriosis. The L1 cell adhesion molecule (L1CAM) is over expressed in ovarian and endometrial carcinomas and is associated with a bad prognosis. Here, we have...

It seems that endometriosis plays an important role in female factor infertility but a clear causal relationship has yet to be established. This case-control study was conducted to determine and compare the frequency and severity of endometriosis in 100 infertile women and 120 fertile multi-para women as control group. Descriptive statistics, Student t test and Chi square test were used in anal...

Clear cell carcinoma of ovary is uncommon ovarian tumour that arises from surface epithelium of ovary. It has well-known association with ovarian endometriosis. We report here the first case of bilateral clear cell carcinoma of ovaries in a 40-year-old woman with a 17-year history of bilateral ovarian endometriosis. In addition, during the longstanding duration of the endometriosis, the patient...

Although the exact etiology is not fully understood, most physicians recognize that endometriosis plays a key role (3). In the literature, this condition is described at thoracic endometriosis (TE), thoracic endometriosis syndrome (TES), or thoracic endometriosis-related pneumothorax (TERP). Documented case studies describe thoracic or pulmonary endometriosis as implants on the lung or pleura (...

Accessible online at: www.karger.com/goi In this issue of Gynecologic and Obstetric Investigation, the review of David Redwine clearly shows that invisible microscopic endometriosis, if well defined and well examined, is very rare [1]. Similar findings have been found in baboons [2], primates with spontaneous endometriosis that represent the best nonhuman primate model to study the pathogenesis...

Background: Endometriosis is one of the most common benign gynecological diseases which is characterized by endometriallike tissue growing outside the uterine cavity. Although the pathology of endometriosis remains unknown, the genetic predisposition plays an apparent role. Several genes have been contributed to endometriosis, but it seems KRAS has a crucial role, because its activation results...

To assess the impact of endometriosis on intracytoplasmic sperm injection (ICSI) outcome, we have retrospectively evaluated 980 ICSI cycles, comparing the results of women with and without endometriosis. A total of 101 cycles was identified in which various degrees of endometriosis were involved, and in the remaining 879 cycles, male infertility was the only cause of infertility. Ejaculated spe...

A potential connection exists between exposure to organochlorine chemicals and the increasing prevalence of endometriosis. Evidence shows that dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin) can increase the incidence and severity of the disease in monkeys and can promote the growth or survival of endometrial tissue implanted into rodents in a surgically induced model of endometriosis. The mechani...

Endometriosis represents a multifaceted disease with controversial pathogenesis. Effective medical therapy for endometriosis is still urgently needed. In this study, we attempted to reveal the association between CCL27 and endometriosis to investigate new approach in the endometriosis etiology and treatment. We examined the expression of CCL27 in endometriotic tissue and serum samples. Then we ...

OBJECTIVE To evaluate the association between endometriosis and chronic endometritis. METHODS Endometrial specimens were obtained from 71 patients, 34 with endometriosis (endometriosis group) and 37 without endometriosis (non-endometriosis group), who underwent hysterectomy, and the specimens were immunostained for the plasmacyte marker CD138. The rate of chronic endometritis was compared bet...