Both the extracellular matrix and parathyroid hormone-related peptide (PTHrP) have been implicated in the differentiation and migration of extra-embryonic endodermal cells in the pre-implantation mammalian blastocyst. In order to define the individual roles and interactions between these factors in endodermal differentiation, we have used embryoid bodies derived from Lamc1(-/-) embryonic stem c...

Basal cell adenocarcinoma is a low-grade malignancy of the salivary glands. minor gland an extremely rare disease that originates from maxillary sinus. The histopathological characteristics basal adenocarcinomas are similar to those adenomas. However, can be differentiated adenomas based on their tendency invade surrounding tissues. Surgical resection first-line treatment for adenocarcinomas. A...

Human embryonic stem cells (hESCs) can provide insights into development of inaccessible human tissues such as embryonic endoderm. Progress in this area has been hindered by a lack of methods for isolating endodermal cells and tracing fates of their differentiated progeny. By using homologous recombination in human ESCs, we inserted an enhanced green fluorescent protein (eGFP) transgene into th...

Isolated or solitary neurofibromas of the paranasal sinuses are rare. Mostly, they involve the maxillary sinus and so far, a solitary neurofibroma of the frontal sinus has never been reported in the literature. We present a case of frontal sinus neurofibroma treated successfully with surgical excision. A 28-year-old male presented with forehead swelling and computed tomography images revealed a...

Postoperative pseudomeningocele is a common complication of craniotomies for tumor resection. Intracranial hypertension can hinder dural repair and potentially lead to refractory or severe cases pseudomeningocele. We present an unconventional use venous sinus stenosis stenting treat postcraniotomy driven by intracranial hypertension.