نتایج جستجو برای: enchondroma

تعداد نتایج: 269  

Journal: :Archives d'anatomie pathologique 1965
M Jermann K Eid T Pfammatter R Stahel

A30-year-old woman presented with painful hemangiomas (Figure, A and B) and enchondromas (Figure, C) in her arms, predominantly in the left hand. The hemangiomas had existed since childhood. They were slowly increasing in size, especially the girth of the left thumb. Multiple resections of enchondromas and transarterial carpal embolizations of the hemangiomas with polyvinyl alcohol particles ha...

Journal: :American journal of clinical pathology 2001
S Söder C Inwards S Müller T Kirchner T Aigner

We studied matrix composition and gene expression pattern in chondromyxoid fibromas on the protein and the messenger RNA levels. We could clearly identify focal chondrocytic differentiation within chondromyxoid fibroma by the expression and deposition of type II collagen, which is a marker of chondrocytic cell differentiation. We also were able to show expression of collagen types I, III, and V...

Journal: :Development 2008
Guan Yang Qiang Sun Yan Teng Fangfei Li Tujun Weng Xiao Yang

Chondrocytes within the growth plates acclimatize themselves to a variety of stresses that might otherwise disturb cell fate. The tumor suppressor PTEN (phosphatase and tensin homolog deleted from chromosome 10) has been implicated in the maintenance of cell homeostasis. However, the functions of PTEN in regulating chondrocytic adaptation to stresses remain largely unknown. In this study, we ha...

Journal: :Genome research 2014
Yasushi Totoki Akihiko Yoshida Fumie Hosoda Hiromi Nakamura Natsuko Hama Koichi Ogura Aki Yoshida Tomohiro Fujiwara Yasuhito Arai Junya Toguchida Hitoshi Tsuda Satoru Miyano Akira Kawai Tatsuhiro Shibata

Chondrosarcoma is the second most frequent malignant bone tumor. However, the etiological background of chondrosarcomagenesis remains largely unknown, along with details on molecular alterations and potential therapeutic targets. Massively parallel paired-end sequencing of whole genomes of 10 primary chondrosarcomas revealed that the process of accumulation of somatic mutations is homogeneous i...

Journal: :Cancer 2007
Akihiko Takeuchi Yasuhiko Yamamoto Koichi Tsuneyama Chunmei Cheng Hideto Yonekura Takuo Watanabe Katsuji Shimizu Katsuro Tomita Hiroshi Yamamoto Hiroyuki Tsuchiya

BACKGROUND Chondrosarcoma, the second most frequent primary malignant bone tumor, is classified into 3 grades according to histologic criteria of malignancy. However, a low-grade lesion can be difficult to distinguish from a benign enchondroma, whereas some histologically low-grade lesions may carry a poor prognosis. The receptor for advanced glycation endproducts (RAGE) and its ligand, high-mo...

Journal: :The Journal of hand surgery 2002
Jacob Bickels James C Wittig Yehuda Kollender Kristen Kellar-Graney Kari L Mansour Isaac Meller Martin M Malawer

Removal by means of curettage is the mainstay of surgical treatment of enchondromas of the hand. Reconstruction traditionally entails filling the tumor cavity with a bone graft, or it may be decided not to perform a reconstruction. In either case a period of protected activity is needed until the tumor cavity has healed. The current study describes the use of cemented internal fixation for the ...

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