It has been one year since Brazil passed a law enabling scientists to work with human embryonic stem cells and to derive new stem cell lines from human embryos. But several major hurdles have put human embryonic stem cell research on hold.

The derivation of human embryonic stem cells 10 years ago ignited an explosion of public interest in stem cells, yet this achievement depended on prior decades of research on mouse embryonic carcinoma cells and embryonic stem cells. In turn, the recent derivation of mouse and human induced pluripotent stem cells depended on the prior studies on mouse and human embryonic stem cells. Both human e...

A biomimetic substrate for cell-culture is fabricated by plasma treatment of a prestressed thermoplastic shrink film to create tunable multiscaled alignment "wrinkles". Using this substrate, the functional alignment of human embryonic stem cell derived cardiomyocytes is demonstrated.

There are four major positions on human embryonic stem cell research in the different member states of the European Union, ranging from permissive to very restrictive. This reflects the diversity of research systems within Europe and poses a challenge to developing a common European research policy.

background: umbilical cord tissue is a very rich source of mesenchymal stem cells. instead of discarding this source we are banking the tissue along with cord blood for possible future cell based applications. the cord tissue needs to be transported and stored properly in order for it to be good enough for cell isolation at a later date. in this paper we have carried out a validation study to d...

introduction : use of adipose-derived stem cells (adscs) is a suggested hypothesis to enhance the regeneration of bone defects. this technique is of particular interest since adscs are more easily accessible via a non-invasive harvesting technique compared to bone marrow stem cells (bmscs). this study sought to assess the efficacy of adsc implantation for regeneration of localized mandibular bo...

A Need for meat is rising day by and the production of poultry, cows, pigs fisheries reduced as there no good commercial production. Wider livestock becoming unavailable on a global scale in requisites welfare animals, ecological sustenance human health conditions. Choices cultured are being explored using innovative techniques like stem cells, Embryonic Stem Cells, Induced pluri potent cells [...

Blastocyst injection and morula aggregation are commonly used to evaluate stem cell pluripotency based on chimeric contribution of the stem cells. To assess the protocols for generating chimeras from stem cells, 8-cell mouse embryos were either injected or cocultured with mouse embryonic stem cells and induced pluripotent stem cells, respectively. Although a significantly higher chimera rate re...

Cover illustration: The cover image is based on the Research Article Repetitive short-pulsed illumination efficiently activates photoactivatable-Cre as continuous in embryonic stem cells and pre-implantation embryos of transgenic mouse by Kanae Kishi et al., https://doi.org/10.1002/dvg.23457.