We would like to thank Serge Mordon and his group for their stimulus to an important discussion, which was one of the aims of our paper to initiate. Our first series of experiments indicate that ELT leads to a wide variation in the effects on tissue within a certain treatment protocol. This may be due to a very complex mechanism of endovenous laser-induced thermal alteration. In ELT, energy lev...

Cells in a developing animal embryo become specified by the activation of cell-type-specific gene regulatory networks. The network that specifies gut nematode Caenorhabditis elegans has been subject study for more than two decades. In this network, maternal factors SKN-1/Nrf and POP-1/TCF activate zygotic GATA factor cascade consisting regulators MED-1,2 → END-1,3 ELT-2,7, leading to specificat...

Ground-conjugate wide eld AO is presented and preliminary performance results are given, which show that signi cant seeing improvement can be achieved over 10-20 arcmin eld of view. A proposal for an ELT AO system is sketched.

Comparative analysis between Caenorhabditis elegans and other nematode species offers a powerful approach to study gene function. C. elegans also has great potential as a surrogate expression system to study the function of genes from parasitic nematode species where transgenic methodologies are unavailable. However there is little information on the extent to which the biology of C. elegans is...

English as a lingua franca (ELF) research highlights the complexity and fluidity of culture in intercultural communication through English. ELF users draw on, construct, and move between global, national, and local orientations towards cultural characterisations. Thus, the relationship between language and culture is best approached as situated and emergent. However, this has chal­ lenged previ...

The importance of digital literacy has grown significantly, making its integration into English language teaching (ELT) crucial. This study investigated the role ELT in promoting among students at Muhammadiyah University Mataram and identified their needs. Using a mixed-methods research design, data were collected from students’ need through questionnaires interviews, which assessed skills, tec...

BACKGROUND Appropriate diagnostic testing involves considerations of cost-effectiveness. We examined the cost-effectiveness of individual tests in a panel of tests defined by the Japan Society of Clinical Pathology. METHODS We studied 540 new, symptomatic primary care outpatients with a set of 30 common diagnostic tests [the Essential Laboratory Tests (2); ELT(2) panel] for clinical evaluatio...

BACKGROUND Blood loss and uncontrollable bleeding are major factors affecting survival in trauma patients. Because treatment with antifibrinolytic drugs may be effective, early detection of hyperfibrinolysis with rotation thrombelastography (ROTEM may be beneficial. METHODS Eighty-seven trauma patients were included in this prospective observational study. Blood samples were collected at admi...