نتایج جستجو برای: elevated plus maze test
تعداد نتایج: 1073624 فیلتر نتایج به سال:
methanol extract of dried leaves of momordica charantia linn ( cucurbitaceae ) was investigated for anxiolytic, antidepressant and anti-inflammatory activities in animal models. anxiolytic activity of methanol extract of dried leaves of momordica charantia linn was tested by elevated plus maze test and the results showed a significant anxiolytic effect comparable, with diazepam in all the teste...
in the current study, we assessed the role of transient receptor potential (trp) channels on avoidance memory and anxiety states in ca3 area of the hippocampus. we explored the anxiety and avoidance memory states using test-retest protocol in the elevated plus maze to understand whether trp channels can affect the above mentioned states in ca3 area. to investigate the consolidation phase of mem...
Latua pubiflora (Griseb) Phil. Is a native shrub of the Solanaceae family that grows freely in southern Chile and is employed among Mapuche aboriginals to induce sedative effects and hallucinations in religious or medicine rituals since prehispanic times. In this work, the pentobarbital-induced sleeping test and the elevated plus maze test were employed to test the behavioral effects of extract...
Elevated anxiety symptoms have been reported to be present in many patients with diabetes mellitus. The underlying mechanisms by which diabetes mellitus influences behavior remain to be determined. We assessed feeding and anxiety behaviors in spontaneously diabetic Ins2Akita mice. We measured blood glucose, body weight, and food and water intakes in C57BL/6 heterozygote Ins2Akita mice. The beha...
Female hooded-Lister rats received either sub-chronic phencyclidine (PCP) (2 mg/kg, n=20) or vehicle (1 ml/kg, n=20) i.p. twice daily for seven days, followed by a sevenday washout period. Rats were challenged with acute PCP or vehicle and tested for locomotor activity to ensure hyperactivity was observed in the sub-chronic PCP treated rats. Rats were then tested on the elevated plus maze and i...
زمینه و هدف: اختلالات اضطرابی از مشکلات عمده بشری است، تحقیق و جستجو بر ای یافتن داروهای مؤثر با عوارض جانبی کمتر ادامه دارد. آویشن شیرازی از گیاهان دارویی با اثرات درمانی گوناگون است که احتمال اثرات ضد اضطرابی برای آن وجود دارد. هدف از این مطالعه بررسی تأثیر رژیم غذایی حاوی برگ آویشن شیرازی بر رفتار اضطراب در موش صحرایی بود. روش بررسی: در این مطالعه تجربی تعداد 40 سر موش صحرایی نر بالغ نژاد وی...
Memory Impairment and Reduced Exploratory Behavior in Mice after Administration of Systemic Morphine
In the present study, the effects of morphine were examined on tests of spatial memory, object exploration, locomotion, and anxiety in male ICR mice. Administration of morphine (15 or 30 mg/kg, intraperitoneally (i.p.)) induced a significant decrease in Y-maze alternations compared to saline vehicle-treated mice. The reduced Y-maze alternations induced by morphine were completely blocked by nal...
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