Objective: IFN-based therapy induces long-term remission in ~20% of CHB-patients. Identification of predictors of treatment response can facilitate the clinical decision. Methods: 168 CHB-patients treated with IFN-based therapy were studied. Predictors of end-of-treatment response (ETR) and sustained response (SR) one-year post therapy were identified by non-parametric chi-square test and corre...

Castanopsis hystrix is a major community-building species in the top communities of southern subtropical China, with high natural regeneration capacity. However, excessive logging and introduction exotic tree have substantially reduced area forest patches hystrix, seedling essential for long-term continuation populations. To explore effects light intensity on emergence early growth shading expe...

Abstract Background The photosynthetic parameters of cotton plants may be modified by the timing film removal during their growing period. This study was undertaken 2015–2017 in Xinjiang, China, to determine what extent mulching time, 1 and 10 days before first irrigation day second after seedling emergence, influenced cotton’s characteristics. control group (CK) film-mulched throughout growth ...

background: both azadirachtin and rotenone, two botanical pesticides have shown inhibit the growth of cultured insect cells. the inhibitory effect of rotenone on cell growth is through disruption of electron transport chain, but exact mechanism of effect of azadirachtin on growth of cell is unknown. this study was carried out to compare the effect of these phytochemical on oxygen consumption by...

The microbial transfer of electrons to extracellularly located solid compounds, termed extracellular electron transport (EET), is critical for microbial electrode catalysis. Although the components of the EET pathway in the outer membrane (OM) have been identified, the role of electron/cation coupling in EET kinetics is poorly understood. We studied the dynamics of proton transport associated w...

The innate proatherosclerotic properties of non-nucleoside reverse transcriptase inhibitors have not previously been examined. Therefore, we performed a pilot study of etravirine (ETR) in healthy volunteers over 28 days. This investigation also allowed us to evaluate the safety of ETR over a period commonly used for HIV postexposure prophylaxis. ETR 200 mg twice daily was given to 28 healthy HI...

INTRODUCTION Etravirine(ETR) can be used for patients who have failed NNRTI-based regimen. In Thailand, ETR is approximately 45 times more expensive than rilpivirine(RPV). However, there are no data of RPV use in NNRTI failure. Therefore, we assessed the susceptibility and mutation patterns of first line NNRTI failure and the possibility of using RPV compared to ETV in patients who have failed ...

Quantum transport in disordered systems has been studied for many years, yet many open problems remain. One focus of these investigations is the interference of inelastic electron scattering due to electron-phonon interaction and elastic electron scattering due to impurities, boundaries and defects. Electron-phonon interaction determines the electron energy loss rate and also manifests itself i...

Production per amount of water used (water use efficiency, WUE) is closely correlated with drought tolerance. Although stomatal aperture can regulate WUE, the underlying molecular mechanisms are still unclear. Previous reports revealed that stomatal closure was inhibited in the calcium-sensing receptor (CAS) antisense line of Arabidopsis (CASas). Here it is shown that decreased drought toleranc...