Abstract Elucidating electrokinetic stability by which surface charges regulate toxins interaction with erythrocytes is crucial for understanding the cell functionality. Electrokinetic properties of human upon treatment Vipoxin, phospholipase A2 (PLA2) and Vipoxin acidic component (VAC), isolated from Vipera ammodytes meridionalis venom were studied using particle microelectrophoresis. PLA2 tre...

The ion selectivity of nanopores due to the wall surface charges is capable of inducing strong coupling between fluidic and ionic motion within the system. This interaction opens up the prospect of operating nanopores as nanoscale devices for electrokinetic energy conversion. However, the very short channel lengths make the ionic movement and fluidics inside the pore to be substantially affecte...

We developed a novel method to increase the sensitivity of standard Enzyme-Linked Immunosorbent Assay (ELISA) using a multiplexed electrokinetic concentration chip. The poly(dimethylsiloxane) (PDMS) molecular concentrator1 was used to trap and collect charged fluorescent product of targetbound enzyme turnover reaction of ELISA that occurred in a standard 96 well plate. Detection sensitivities o...

Clinical and point-of-care disease diagnostics promise to play an important role in personalized medicine, new approaches to global health, and health monitoring. Emerging instrument platforms based on lab-on-a-chip technology can confer performance advantages successfully exploited in electrophoresis and electrochromatography to affinity-based electrokinetic separations. This review surveys la...

We describe a novel method that exploits electrokinetic streaming current measurements for the study of ion-interface affinity. Through the use of liquid microjets and ultradilute solutions (<1 μM), we are able to overcome inherent difficulties in electrokinetic surface measurements engendered by changing double-layer thicknesses. Varying bulk KCl concentrations produce statistically significan...

This study reports a multifunctional electrode approach which directly implements electrokinetic enhancement on a self-assembled-monolayer-based electrochemical sensor for point-of-care diagnostics. Using urinary tract infections as a model system, we demonstrate that electrokinetic enhancement, which involves in situ stirring and heating, can enhance the sensitivity of the strain specific 16S ...

Electrokinetic behavior in synthetic process of composite particles have been analysed under the different combination systems. Firstly, the heterocoagulation process of amphoteric polymer latices on spherical silica was investigated as a function of z-potential of component particles, particle size ratio and of electrolyte in the medium. On the basis of these data, subsequent experiments to pr...

AC electrokinetics is a versatile tool for contact-less manipulation or characterization of cells and has been widely used for separation based on genotype translation to electrical phenotypes. Cells responses to an AC electric field result in a complex combination of electrokinetic phenomena, mainly dielectrophoresis and electrohydrodynamic forces. Human cells behaviors to AC electrokinetics r...