RNA interference-mediated gene silencing offers the potential of targeted inhibition of disease-relevant genes. In vivo delivery of RNAi reagents can be obtained by a variety of approaches. Physical delivery methods appear safer and lack side effects. Electro-permeabilization is one of the non-viral methods successfully used to transfer small interfering RNAs (siRNAs) in vitro and in vivo. A pr...

introduction:owing to its favorable radionuclidic characteristics, such as tl/2 = 6.73 day and eβ (max) = 497 kev and ease of its large-scale production using medium flux research reactors, lutetium-177 (177lu) is an attractive radionuclide for various therapeutic applications. no carrier added (nca) 177lu was obtained by thermal neutron bombardment (4×1013n/cm2.s) of 176yb target through 176yb...

in the present study, ptruce/mwnts nanocatalysts synthesized via polyol process technique are applied as anode electro-catalyst in methanol electro-oxidation reaction (mor). to characterize the nanocatalysts, tem, xrd, eds and xps are investigated. cyclic voltammetry and choronoamperometry are used to evaluate the electro-catalytic activity and stability of the catalysts in methanol electro-oxi...

Electro-hydraulic systems with regards to the their specific features and applications among other industrial systems including mechanical, electrical and pneumatic systems, have been widely taken into consideration by the scientists and researchers. Due to the fact that the electro-hydraulic system is inherently a nonlinear system, has some problems such as signals saturation, nonlinear effici...

The objective of this study was to assess the efficacy and safety of electroacupuncture in 138 patients with earthquake-caused PTSD using Randomized Controlled Trials (RCTs). 138 cases enrolled were randomly assigned to an electro-acupuncture group and a paroxetine group. The electro-acupuncture group was treated by scalp electro-acupuncture on Baihui (GV 20), Sishencong (EX-HN 1), Shenting (GV...

Characteristics of nanosized Pt electro-catalyst deposited on carbon nanotubes (CNTs) were studied with CO-stripping voltammogram and chronoamperometry measurements. The CNTs were pretreated by oxidation in HNO3, mixed HNO3 + H2SO4 and H2SO4 + K2Cr2O7 solution, respectively, to enable surface modification. Well-homogenized Pt particles (average size: 3 nm) were loaded onto the pretreated CNT sa...

Acupuncture and moxibustion have been shown to be effective in treating Crohn's disease (CD), but their therapeutic mechanisms remain unclear. Here we compared brain responses to either electro-acupuncture or moxibustion treatment in CD patients experiencing remission. A total of 65 patients were randomly divided into an electro-acupuncture group (n = 32) or a moxibustion group (n = 33), and tr...

The clavicle is the most frequently fractured bone in humans. General anesthesia with or without Regional Anesthesia (RA) used for surgeries due to its complex innervation.