While de Lorgeril and Salen [1] call for a new paradigm excluding cholesterol, Trevisan and Stranges [2] call cholesterol lowering [to reduce mortality] ‘‘a great success story!’’ How to reconcile these points of view? The ‘statin success’ story is largely from nonfatal endpoint studies that may well derive much of such benefit from reduced angina (and thus hospital visits and resulting interve...

The incidence of ovarian carcinoma increases with advancing age, peaking during the 7th decade of life and remaining elevated until age 80 years. Despite the high prevalence of ovarian cancer in the elderly, the management of these patients is often less aggressive than that of their younger counterparts. As a result, many elderly cancer patients receive inadequate treatment. However, data do n...

The increasing poverty rate for elderly women is a growing concern in Japan and is generally due to their lifestyle changes and the public pension system based on the pre-1980s (old) lifestyle. At that time, women were expected to get married and become homemakers. Therefore, the public pension system is generous for married women and widows but not for never-married and divorced women. Using a...

OBJECTIVE To assess the relative importance of osteoporosis of the os calcis, cognisance, and mobility in the risk of subsequent fracture of the hip in elderly women. DESIGN Prospective study of elderly women in residential care over two years. SETTING 21 Private or 38 local authority residential homes for the elderly and 4 geriatric hospitals in Doncaster and Hull. SUBJECTS 1414 Ambulant...

cord blood), women 25 to 32 years old (young women group), and women more than 75 years old (elderly women). The frequency of skewed X inactivation in polymorphonuclear cells (PMNs) increased with age: in fact, a cleavage ratio of at least 3.0 was found in 3 of 36 cord blood samples, 5 of 30 young women, and 14 of 31 elderly women. The inactivation patterns found in T lymphocytes were significa...