Hypertension is a common risk factor for peripheral arterial disease (PAD). Guidelines suggest treating PAD patients to a blood pressure 130/80 mm Hg; therefore, our objective was to explore whether attainment of this target blood pressure is associated with improved outcomes. We performed a post hoc analysis of the INternational VErapamil-SR/Trandolapril STudy, a randomized clinical trial, whi...

Atherosclerotic arterial occlusive disease affecting the lower extremities is also known as peripheral artery disease (PAD). This disorder affects 8 to 12 million individuals in the U.S. and is increasingly prevalent in Europe and Asia. Unfortunately, most patients are not diagnosed and are not optimally treated. A blood test for PAD, if sufficiently sensitive and specific, would be expected to...

BACKGROUND Peripheral artery disease (PAD), a manifestation of systemic atherosclerosis that produces blockages in the arteries supplying the legs, affects approximately 5% of Americans. We have previously, demonstrated that a myopathy characterized by myofiber oxidative damage and degeneration is central to PAD pathophysiology. OBJECTIVES In this study, we hypothesized that increased oxidati...

Peripheral arterial disease (PAD) commonly results from the narrowing of peripheral arteries due to atherosclerosis. It is increasing in type 2 diabetes mellitus (DM) patients worldwide; including in Thai type 2 DM patients. This case-control study aims to compare the differences in factors influencing the presence of PAD between type 2 DM patients with and those without PAD and to examine thre...

In a recent paper Cabay et al. 1996a], the authors develop a fast, iterative, look-ahead algorithm for numerically computingPad e-Hermite systems and simultaneous Pad e systems along a diagonal of the associatedPad e tables. Included there is a detailed error analysis showing that the algorithm is weakly stable. In this paper, we describe a Fortran implementation, VECTOR PADE, of this algorithm...

Correspondence: Fred Burbank Salt Creek International Women’s Health Foundation, 1235 Puerta del Sol, Suite 700, San Clemente, CA, 92673, USA Tel +1 949 496 0026 Fax +1 949 492 0650 Email [email protected] Purpose: Two parallel-design, randomized, sham-controlled clinical trials were conducted to study the safety and efficacy of vibratory stimulation (VS) on restless legs syndrome (RLS) patients...

We present the design, development and fabrication of an anatomically accurate, inhomogeneous, elastomeric cardiac model for in vitro testing of cardiac devices. Segmentation of clinical data was performed with Mimics software (Materialise). Mold creation and optimization was performed in 3-Matics (Materialise) using the tooling module. A total of twenty-one molds were designed including sixtee...

BACKGROUND Most older adults with urinary incontinence use absorbent pads. Because of exposure to moisture and chemical irritating substances in urine, the perineal skin region is always at risk for development of incontinence-associated dermatitis (IAD). The aim of this study was to examine the efficacy of an improved absorbent pad against IAD. METHODS A cluster randomized controlled design ...

OBJECTIVE Peripheral arterial disease (PAD) is associated with high rates of morbidity and mortality and serves as an important marker for advanced systemic atherosclerosis accompanied by symptomatic or asymptomatic ischemia of the coronary, cerebral, and visceral vasculature. There are little published data on the use of health care resources and costs attributable to PAD. The objectives of th...