pseudomonas aeruginosa is a leading cause of bum infections, and antibiotic- resistant strains of this bacterium are emerging due to extensive application of antibiotics in the bum unit of hospitals. in this study 50 strains of p. aeruginosa were isolated from bum patients infected with this micro-organism in the bum unit of a general hospital in kerman, iran over one year [may 1999-aprii2000]....

Based on first principles calculations and self-consistent solution of the linearized Boltzmann-Peierls equation for phonon transport approach within a three-phonon scattering framework, we characterize lattice thermal conductivities k of freestanding silicene, germanene and stanene under different isotropic tensile strains and temperatures. We find a strong size dependence of k for silicene wi...

A nano/ultra-fine grain Al-0.2wt% Zr alloy was produced by accumulated roll bonding (ARB) processafter 10 cycles. The fraction of high angle grain boundaries increased from 8% to 65.4% during 10passes during ARB process. This alloy was subjected to tensile test at different temperatures (523,573and 623 K) and strain rates (0.1 and 0.01 s-1). The optimum condition of temperature and strain rate ...

BACKGROUND AND PURPOSE The detailed mechanisms of cerebral aneurysm generation remain unclear. Our aim was to investigate whether specific hemodynamic insult in combination with arterial wall degeneration leads to the development of aneurysms in a canine model. MATERIALS AND METHODS New branch points in the common carotid artery were created in 18 dogs. Nine animals subsequently received elas...

AIMS CD163 is a macrophage receptor for haemoglobin-haptoglobin (Hb-Hp) complexes, responsible for the clearance of haemoglobin. We hypothesized that production of soluble CD163 (sCD163) may be due to proleolytic shedding of membrane CD163 by neutrophil elastase, reported to be increased in culprit atherosclerotic plaques. We analysed the relationship between CD163 solubilization and elastase i...

Inflammatory responses have been known to contribute to the development of neuronal damage after brain ischemia in experimental animals. Also, neutrophil elastase activity in the plasma has been elevated in the patients with acute cerebral infarction. In order to clarify whether neutrophil elastase distributes into the brain parenchyma and exacerbates neuronal damage following ischemia, we exam...

Finite strain and vorticity analyses were carried out in the deformed conglomerate and micro-conglomerate of Goushti shear zone in the Sanandaj-Sirjan metamorphic belt (Zagros Mountains Iran). These deformed rocks are bounded between two NE and SW major thrust faults. Finite strain measurements on three principal planes of strain ellipsoid show the higher amounts of strain ratios near the major...

Serum elastase and its inhibitors were determined in the sera of heavily burnt patients. Serum elastase levels were elevated at two to eight days after a severe burn-accident and returned towards normal values from the 10th day on. Both alpha1-antitrypsin and alpha2-macroglobulin levels were also elevated in the sera of heavily burnt patients. alpha1-Antitrypsin showed a parallel evolution to t...

During blood coagulation. polymorphonuclear leukocytes release elastase in amounts that can exceed 100 nmol/L. We therefore studied the interaction between human leukocyte elastase and human a-thrombin. Elastase cleaved the thrombin B chain (Ala 1 50-Asn 1 51 ) near the “y-cleavage site, resulting in two fragments held together by noncovalent interactions. The NH2-terminal fragment (Fl). mol wt...

The mouse genome contains a family of clan C1A proteases that appear to be restricted to rodents within Eutherian (placental) mammals. mRNA analysis has shown that these genes are expressed exclusively in placenta. Sequence analysis predicts that the expressed proteins will be functional and consequently it was proposed that this family of proteases may have evolved to perform subspecialized fu...