Technologies have started to overlap new virtual communication and information layers on top of the urban physical territory, thus bringing along distinct possibilities of social organization. Regarding this phenomenon and intending to achieve improvement in a great variety of fields from Politics to Urban Planning, the terms of Smart or Digital Cities among others have been adopted, still with...

289 Dutch population, on average, has changed plans each year. Moreover, accelerating consolidation of the health insurance market has restricted meaningful choice of insurance plan. Currently, four insurance conglomerates control about 90% of the Dutch health insurance market. Recent polls suggest public dissatisfaction with private insurers, with 65% of insured people reporting that they have...

ulation of hematopoietic lineage differentiation in mammals (Chen et al., 2004), and control of leaf and flower trolled by miRNAs indicate that these examples represent a very small fraction of the total This review highlights what has been learned about MicroRNAs (miRNAs) are endogenous ‫22ف‬ nt RNAs that can play important regulatory roles in animals and miRNAs in the decade since the report ...

Global climate change draws the attention of governments at every level, from the village board to the U.N. Security Council. At the international level, the U.N. Framework Convention on Climate Change (UNFCCC) has been the hub of efforts to address the threat of climate change. But over time, many other international institutions have become engaged in climate-related work. Indeed, one recent ...

3 3 AS S OCIE T Y REL IES more on nonprofit organizations to p r ovide critical services, advocate for public policy, and stimulate innovation, leaders in the nonprofit sector share common concerns: how to make better use of limited resources in the face of growing need; how to increase the accountability of nonprofits to donors and regulators; and how to stay the course and reach established g...

The number of space objects monitored by USSPACECOM up to geostationary altitudes is on the order of 10,000. These objects need to be larger than 10 to 30 cm in order to be operationally trackable and identifiable. At present, the only nations with an operational space surveillance capability, and with a routinely updated space object catalog, are the USA and Russia. For several applications, E...

Over the past fifteen years, our perspective on tackling information interoperability problems for web-based scholarship has evolved significantly. In this opinion piece, we look back at three efforts that we have been involved in that aptly illustrate this evolution: OAI-PMH, OAI-ORE, and Memento. Understanding that no interoperability specification is neutral, we attempt to characterize the p...

We examine the optimal choice of hurdle rates in a capital budgeting setting in which a manager receives superior information regarding the profitability of an investment project. Unlike the prior capital budgeting literature that treats the distribution of investment returns as exogenous, we consider a scenario in which the manager can engage in upfront project development activities to improv...

‘FastContact’ is a server that estimates the direct electrostatic and desolvation interaction free energy between two proteins in units of kcal/mol. Users submit two proteins in PDB format, and the output is emailed back to the user in three files: one output file, and the two processed proteins. Besides the electrostatic and desolvation free energy, the server reports residue contact free ener...