Background MR Fingerprinting (MRF) [1] offers a novel approach for quantifying extracellular volume (ECV) in a single scan without contrast agent. Whereas conventional parameter mapping assumes chemical exchange occurs much faster than the experiment time scale, usually on the order of T1, MRF measurements are acquired every TR (less than 12ms). This project investigates the feasibility of a ne...

Methods Short-axis T1 and T2 mapping were implemented into a standard CMR protocol at 1.5 Tesla in 36 patients with clinically suspected myocarditis. T1 quantification was performed for ECV calculation using the modified Look-Locker inversion-recovery (MOLLI) sequence before and 15 minutes after administration of 0.075 mmol/kg gadolinium BOPTA. T2 quantification was performed using a free-breat...

Methods In 25 patients (age 13.6±2.5 years, 14 male) after surgical repair of Tetralogy of Fallot (ToF), T1 measurements were performed at a mid and basal ventricular level in short axis before and 15 minutes after the application of 0.1 mmol/kg gadobenate dimeglumine in the interventricular septum (IVS), left ventricular (LV) lateral wall, complete LV myocardium and diaphragmatic portion of th...

BACKGROUND In this study, the authors cultivated ECV-304 in vitro and incubated cells with H2O2, established injury models, and induced oxidized endothelial cell apoptosis. This model makes it possible to choose suitable concentrations of North Schisandra Lignans. OBJECTIVE To study the protective effects of North Schisandra Lignans on human umbilical vein endothelial cell injuries. METHODS...

Background Although cardiac magnetic resonance (CMR) imaging is routinely used for evaluation of patients with repaired tetralogy of Fallot (TOF), the role of extracellular volume (ECV) measurement, a marker of diffuse myocardial fibrosis, has not been studied extensively in this population. This study aimed to describe left ventricular (LV) ECV measurements in subjects with repaired TOF, and t...

Background Myocarditis subsumes a variety of entities, including diverse courses from complete healing to dilated cardiomyopathy with severe myocardial fibrosis. T1-mapping cardiovascular magnetic resonance (CMR) has the ability to quantify myocardial extracellular volume (ECV) as a surrogate of acute and chronic myocardial injury. Galectin-3 is an important mediator of fibrogenesis and contrib...

Background T1 Mapping has emerged as a new marker to quantify myocardial extracellular volume (ECV), which is typically increased in the setting of diffuse fibrosis or infiltrative heart diseases. However the reproducibility of the technique is largely unknown. We sought to identify the interobserver, intraobserver variability of different T1 mapping techniques as well as validation of one tech...

La enfermedad periodontal y los trastornos sistémicos continúan siendo un problema de salud pública a nivel mundial. En últimos años, varios estudios han evidenciado una asociación entre la periodontitis las enfermedades cardiovasculares (ECV). Por lo tanto, el objetivo presente revisión bibliográfica es determinar ECV. Se realizó exhaustiva literatura en idioma inglés para recopilar publicacio...

Background Extracellular volume (ECV) calculated from T1 maps can quantitatively characterize myocardial tissue, including the severity of tissue damage in myocardial infarction (MI) (1). An alternative approach for measuring the density of MI may be to calculate the relative signal intensity of LGE images.) A direct comparison of signal intensity of LGE and ECV in MI has not been carried out. ...

Background Cardiac imaging in obese adults poses significant technical challenges, yet the prognostic value of diffuse myocardial fibrosis in obese adults quantified with cardiovascular magnetic resonance (CMR) extracellular volume fraction (ECV) measures is unknown. This issue is important because obesity increases the risks of death and hospitalization for heart failure (HHF). Myocardial fibr...