In the present report, A-V dissociation with concealed retrograde conduction into the A-V node, caused SINUS beats to exhibit antegrade A-V nodal conduction delay sufficient to result in episodes of supraventricular tachycardia (SVT). In this patient, atrial ectopic premature depolarizations were never observed. The primary role of A-V nodal conduction delay in the genesis of paroxysmal SVT is ...

BACKGROUND Postoperative junctional ectopic tachycardia (JET) occurs frequently after pediatric cardiac surgery. R-wave synchronized atrial (AVT) pacing is used to re-establish atrioventricular synchrony. AVT pacing is complex, with technical pitfalls. We sought to establish and to test a low-cost simulation model suitable for training and analysis in AVT pacing. METHODS A simulation model wa...

Atrial fibrillation (AF) is certainly the most common arrhythmia encountered in clinical practice, reaching epidemic proportions in occidental society. Nowadays, transcatheter ablation using radiofrequency (RF) has become a popular technique in the treatment of drug-resistant AF. Since ectopic beats originating from the pulmonary veins (PVs) have been shown to be the main trigger initiating AF,...

We describe a patient who presented with the syndrome of inappropriate antidiuretic hormone secretion (SIADH) 2 months before clinical evidence of bronchogenic malignancy. Because of the potential for the ectopic production of atrial natriuretic peptide (ANP) to mimic SIADH, both hormones were measured in this hyponatremic patient to seek a possible marker of tumor activity. A hypertonic saline...

In many high complexity systems (cells, organisms, institutions, societies, economies, etc.), it is unclear which components should be regulated to affect overall performance. To identify and prioritize molecular targets which impact cellular phenotypes, we have developed a selection procedure ("SPI"-single promoting/inhibiting target identification) which monitors the abundance of ectopic cDNA...

Synaptic target selection is critical for establishing functional neuronal circuits. The mechanisms regulating target selection remain incompletely understood. We describe a role for the EGF receptor and its ligand Gurken in target selection of octopaminergic Type II neurons in the Drosophila neuromuscular system. Mutants in happyhour, a regulator of EGFR signaling, form ectopic Type II neuromu...

AIMS The aim of this study was to evaluate the mechanisms of induction of paroxysmal atrial fibrillation (PAF) by analysis of its onset recorded on Holter monitoring (HM). METHODS AND RESULTS One hundred and seven HM were evaluated in 90 patients (mean age 67.7, cardiac disease in 31.1%), with one or more self-terminating episodes of PAF, lasting >or=30 s. Two hundred and thirty-three episode...

Atrial fibrillation (AF) persists as the most challenging arrhythmia in clinical practice, and it currently affects an estimated 400 million people worldwide. We view AF as the most common sustained supraventricular tachyarrhythmia, for it is associated with extensive morbidity and mortality [1]. According to some studies, AF is responsible for numerous hospitalizations, which result in signifi...

Patient aged 42, Caucasian, asymptomatic, with family history of HCM and diagnosis of the same cardiomyopathy 22 years ago. The 24-h Holter heart rhythm monitoring (April 5, 2012) showed sinus rhythm, rare atrial ectopic beats, presence of 2,970 isolated ventricular extrasystoles and five outbreaks of non-sustained ventricular tachycardia (NSVT), the longest one presenting 13 QRS complexes. Giv...

The common atrioventricular nodal re-entry tachycardia is the most common form of paroxysmal supraventricular tachycardia. It starts frequently with a supraventricular ectopic beat that, on finding the fast pathway in refractory period, travels in the slow pathway as to appear as a prolongation of the PR interval on the ECG. In this study, we show a singular case of a common atrioventricular no...