Poromas are uncommon benign neoplasms originating from the terminal ductal portion of the sweat glands, mainly characterized by skin-colored or pink papules or nodules, usually on the extremities. Due to their rarity, the pigmented form clinical hypothesis is hardly ever suggested and psychopathology is fundamental. We report a case of pigmented eccrine poroma in the right palmer area, a locati...

ECTODERMAL DYSPLASIA IS A RARE DISORDER WITH DEFECTS IN TWO OR MORE OF THE FOLLOWING STRUCTURES: the teeth and the skin and its appendages including hair, nails, eccrine, and sebaceous glands. Anhidrotic ectodermal dysplasia is the most common type of disease. This rare disorder, also known as Christ-Siemens-Touraine syndrome, manifests as a triad of hypotrichosis, asteatosis, and anhidrosis. I...

© 2009 The Authors. doi: 10.2340/00015555-0696 Journal Compilation © 2009 Acta Dermato-Venereologica. ISSN 0001-5555 Sir, Topiramate (TPR) is an adjunctive treatment for patients with refractory epilepsy. Several cases of hypohidrosis under TPR treatment have been reported. We describe here a new reversible side-effect on human sweating function: blue pseudochromhidrosis. Chromhidrosis and pseu...

cording to their histology, and imaging examinations are not routinely performed. However, when a large soft tissue mass exists and malignancy is suspected, then imaging may be helpful to scrutinize the nature of the tumor. Malignant nodular hidradenoma is a rare aggressive malignant tumor of the eccrine sweat glands. Approximately 50 cases had been documented up to the year 2004 in the English...

1. In the epidermis non-specific esterase activity outlines a strongly reactive band between the stratum granulosum and the stratum corneum. In the epidermis of the palm, there is no such esterase-rich band. 2. The outer sheath of active hair follicles has strong enzyme activity. The degenerating hair bulb in catagen follicles is very strongly reactive, and clusters of cells around the hair clu...

Human skin consists of a stratified, cellular epidermis and an underlying dermis of connective tissue [1–5]. The dermal–epidermal junction is undulating in section; ridges of the epidermis, known as rete ridges, project into the dermis. The junction provides mechanical support for the epidermis and acts as a partial barrier against exchange of cells and large molecules. Below the dermis is a fa...

Sir, Unilateral localized hyperhidrosis is an uncommon condition with diverse causes. Lesions affecting any part of the sympathetic nervous system are often encountered as the cause of the disease and in a few cases enlarged sweat glands have been shown; these cases have been regarded as a type of eccrine naevi. There are also some cases in which the underlying pathology cannot be determined, a...

In this case report we will describe a rare association between anhyrotic ectodermal dysplasia (AED) and immunodeficiency and autoimmunity [in our case: Idiopathic Thrombocytopenic Purpura (ITP) and Crohn disease]. AED is a rare congenital disorder characterized by sparse hair, abnormal teeth and anhidrosis due to lack of eccrine glands. The survey of 87 cases with (AED) revealed only one Irrit...

The functional activity of the eccrine sweat glands in the toe-pads of non anesthetized dogs was investigated. Spontaneous sweating of central origin was found to be considerable in dogs in early months (within 1-3 months) of birth. This sweating was easily blocked by local administration of atropine, but not by dihydroergotamine, indicating a cholinergic nerve supply to the sweat glands. The r...

In a sibship of ten, three brothers presented with an adult form of ceroid-lipofuscinosis. The diagnosis was confirmed by necropsy of the first patient and was made by electron microscopy of eccrine sweat glands and of skeletal muscles in the two others. Somatosensory evoked potentials were characterised by biphasic, nearly monophasic, very high voltage complexes totally unlike those found in n...