Transcatheter aortic valve replacements (TAVRs) are a percutaneous alternative to surgical aortic valve replacements and are used to treat patients with aortic valve stenosis. This minimally invasive procedure relies on expansion of the TAVR stent to radially displace calcified aortic valve leaflets against the aortic root wall. However, these calcium deposits can impede the expansion of the de...

INTRODUCTION Nitric oxide (NO) signaling regulates many biological processes in skeletal muscle, wherein aberrant signaling contributes to myopathic conditions (e.g., Duchenne muscular dystrophy). NO has been shown to play a role in muscle regeneration after injury. However, less is known about its role during injury. In this study we aimed to determine whether NO synthase (NOS) inhibition exac...

the purpose of this study was to examine the effect of indomethacin on biochemical, functional and external symptoms of delayed onset muscle soreness (doms) following eccentric exercise. for this purpose, 20 untrained, healthy male volunteers (age 25.8+6.9 years and fat 15.9+9.3 %) were selected and randomly divided into experimental (n=10) and placebo (n=10) groups. in a double blind study, su...

inflammation and pain induced by delayed onset muscle soreness (doms) can be induced by eccentric exercise or an unaccustomed activity. the condition can causes problems in exercising and for athletes. the purpose of this study was to assess the effect of 150mg curcumin supplementation immediately after intensive eccentric exercise. evaluations were made for total antioxidant capacity (tac), mu...

We present explicit formulae for the eccentric connectivity index and Wiener index of 2-dimensional square and comb lattices with open ends. The formulae for these indices of 2-dimensional square lattices with ends closed at themselves are also derived. The index for closed ends case divided by the same index for open ends case in the limit N →&infin defines a novel quantity we call compression...

INTRODUCTION This study quantified bone removed to correct three different sizes of posterior glenoid defects and also quantified the change in rotator cuff muscle length resulting from correction of each defect using three different glenoid designs. METHODS A 3-D computer model quantified the cortical and cancellous bone removed when correcting three sizes of posterior glenoid defects and si...

1. One common soft-tissue injury in sports involving sprinting and kicking a ball is the hamstring strain. Strain injuries often occur while the contracting muscle is lengthened, an eccentric contraction. We have proposed that the microscopic damage to muscle fibres that routinely occurs after a period of unaccustomed eccentric exercise can lead to a more severe strain injury. 2. An indicator o...

BACKGROUND Recent years, lots of scientific studies are focused on the possible mechanism of inflammatory response and oxidative stress which are the mechanism related with tissue damage and exercise fatigue. It is well-known that free oxygen radicals may be induced under invitro conditions as well as oxidative stress by exhaustive physical exercise. OBJECTIVES The aim of this study was to in...

BACKGROUND Left ventricular hypertrophy (LVH; high LV mass [LVM]) is traditionally classified as concentric or eccentric based on LV relative wall thickness. We evaluated the prediction of subsequent adverse events in a new 4-group LVH classification based on LV dilatation (high LV end-diastolic volume [EDV] index) and concentricity (mass/end-diastolic volume [M/EDV](2/3)) in hypertensive patie...

Conventional vestibular rotation testing with the head centered on the axis stimulates the semicircular canals evoking compensatory eye movements. If the head is placed forwards of the axis in an eccentric position the otoliths are also stimulated by a tangential linear acceleration acting laterally to the skull. In normal subjects the additional otolithic stimulus evokes compensatory eye movem...