Introduction: The objective of this study is to determine the major causes of early death in acute lymphoblastic leukemia (ALL).  Methods: The following databases including PubMed, EMBASE, Science Direct and Google Scholar were searched for following terms: “acute lymphoblastic leukemia”, “early mortality”, “early death “ and “death in induction phase “. Inclusion criteria were all studies abo...

Background: Introduction: Searching for an ideal marker for diagnosing neonatal infection is still an important concern in every country. There are many biomarkers reported for neonatal sepsis. Haptoglobin is an acute phase reactants which rise in response to infection and injuries. In this report we discussed the efficacy of serum haptoglobin level in different cut off levels in early onset ne...

The neuronal cell death associated with perinatal asphyxia, or hypoxicischemic (HI) brain injury, plays an important role in neonatal mortality and neurodevelopment retardation. The types of cell death associated with HI in the brain have been classified as being either apoptotic or necrotic. Here we describe the recent discoveries of multiple non-apoptotic cell death pathways: necroptosis; fer...

Objectives: To summarize the clinical characteristics, and maternal and neonatal outcomes in patients who were diagnosed with acute fatty liver of pregnancy (AFLP). Methods: A retrospective case series study over 10 years was conducted at the Nantong Third People’s Hospital, Nantong University, China. Seven cases diagnosed as AFLP were included. The medical records were reviewed for clinical pr...

BACKGROUND The number, rates and causes of early neonatal deaths in South Africa were not known. Neither had modifiable factors associated with these deaths been previously documented. An audit of live born infants who died in the first week of life in the public service could help in planning strategies to reduce the early neonatal mortality rate. METHODS The number of live born infants weig...

BACKGROUND Few studies have examined fetal, infant and maternal mortality and morbidity among pregnant women at very early gestation with an open cervix and prolapsed membranes. We carried out a study describing the outcomes of women hospitalized with prolapsed membranes at 22-28 weeks' gestation. METHODS We prospectively recruited women with singleton pregnancies admitted at 22-28 weeks' ges...

Methods Pregnancy and neonatal outcomes and placental histopathology reports, from cesarean deliveries (CD) of pregnancies with placenta previa (n=119), between 2009-2015, were reviewed. Results were compared to CD matched for maternal age and pregnancy complications (control group). Placental lesions were classified into maternal and fetal vascular supply lesions, and inflammatory response. Co...

background: introduction: searching for an ideal marker for diagnosing neonatal infection is still an important concern in every country. there are many biomarkers reported for neonatal sepsis. haptoglobin is an acute phase reactants which rise in response to infection and injuries. in this report we discussed the efficacy of serum haptoglobin level in different cut off levels in early onset ne...

OBJECTIVE Clinical studies demonstrate the efficacy of interventions to reduce neonatal deaths, but there are fewer studies of their real-life effectiveness. In India, women often seek facility delivery after complications arise, rather than to avoid complications. Our objective was to quantify the association of facility delivery and postnatal checkups with neonatal mortality while examining t...