In the structure of bovine F(1)-ATPase inhibited with residues 1-60 of the bovine inhibitor protein IF(1), the α-helical inhibitor interacts with five of the nine subunits of F(1)-ATPase. In order to understand the contributions of individual amino acid residues to this complex binding mode, N-terminal deletions and point mutations have been introduced, and the binding properties of each mutant...

Globally each year, 5%e10% of adults and 20%e30% of children experience influenza infections [1]. During the 2009e2010 H1N1 influenza pandemic, these rates were higher and children and adolescents were disproportionately affected [2]. Specifically, in the United States this pandemic was estimated to have caused 86,000 hospitalizations and 1,280 deaths among children 0e17 years of age [2]. World...

Human induced pluripotent stem (iPS) cells hold great promise for cardiovascular research and therapeutic applications, but the ability of human iPS cells to differentiate into functional cardiomyocytes has not yet been demonstrated. The aim of this study was to characterize the cardiac differentiation potential of human iPS cells generated using OCT4, SOX2, NANOG, and LIN28 transgenes compared...

BACKGROUND AND PURPOSE The pattern of antenatal brain injury varies with gestational age at the time of insult. Deep brain nuclei are often injured at older gestational ages. Having previously shown postnatal hypertonia after preterm fetal rabbit hypoxia-ischemia, the objective of this study was to investigate the causal relationship between the dynamic regional pattern of brain injury on MRI a...

In this paper we evaluate the empirical performance of a medium–scale DSGE model (Smets andWouters 2007) when agents form expectations about forward variables by using small forecasting models. Agents learn about these simple AR and VAR forecasting models through Kalman filter estimation and they combine them either using a prediction basedweighting scheme or fixed weights. The results indicate...

This article studies the features of co-movements of prices and production between six CEECs recently joined the EU and the euro zone. More precisely, based partially on the methodology suggested by Alesina, Barro and Tenreyro [2002], we evaluate the size and the persistence of prices and outputs shocks between each CEECs and euro zone. Results will contribute to the debate around the participa...

Helisoma trivolvis embryos display a cilia-driven rotational behavior that is regulated by a pair of serotonergic neurons named ENC1s. As these cilio-excitatory motor neurons contain an apical dendrite ending in a chemosensory dendritic knob at the embryonic surface, they probably function as sensorimotor neurons. Given that nitric oxide (NO) is often associated with sensory neurons in inverteb...

A mechanism for the generation of subsurface cyclones and jets when a warm ring smashes onto a continental slope and shelf is proposed based on the results of a primitive-equation three-dimensional numerical model. The warm ring initially ‘sits’ over a slope with an adjoining shelf in a periodic channel, and its subsequent evolution is examined. The ‘inviscid’ response is cyclonic ‘peeling-off’...

The effect of traffic on the content of lead and cadmium in grass morphological parts-leaves, shoots, and inflorescences-was studied. The samples were taken on a part of the European route E30 (Siedlce by road). The following plants were tested: Dactylis glomerata, Arrhenatherum elatius, and Alopecurus pratensis. During the flowering of grasses, the plant material was collected at distances of ...