Papillomaviruses are small DNA viruses which establish persistent infection in the epithelial tissue of various animal species. Three papillomavirus proteins encoded by the bovine papillomavirus type 1 E2 open reading frame have a common C-terminal DNA binding and dimerization domain and function as dimeric proteins in the regulation of viral gene expression, genome replication, and maintenance...

This study was investigated the effects of dietary estradiol-17? (E2) on growth, body composition and blood indices in Acipenser stellatus. Fish (40.9 ? 1.1 g average initial weight; n = 60 per group) were fed with three different diets containing 0 (control), 25 and 50 mg kg-1 dietary estradiol contents to apparent satiation for seven months. The results suggested that growth rate were decreas...

The E2 protein segregates episomal bovine papillomavirus (BPV) genomes to daughter cells by tethering them to mitotic chromosomes, thus ensuring equal distribution and retention of viral DNA. To date, only the BPV1 E2 protein has been shown to bind to mitotic chromosomes. We assessed the localization of 13 different animal and human E2 proteins from seven papillomavirus genera, and we show that...

The viral E2 gene product plays a crucial role in the human papillomavirus (HPV) vegetative cycle by regulating both transcription and replication of the viral genome. E2 is a transcriptional repressor of the E6 and E7 viral oncogenes for HPV types 16 and 18, which are involved in cervical cancers. Using new polyclonal antibodies against the HPV16 E2 protein, we showed that E2 is expressed at v...

17 -Estradiol (E2) and selective estrogen receptor modulators (SERMs), such as tamoxifen, mediate numerous effects in the brain, including neurosecretion, neuroprotection, and the induction of synaptic plasticity. Astrocytes, the most abundant cell type in the brain, influence many of these same functions and thus may represent a mediator of estrogen action. The present study examined the regul...

Absence of the leucine zipper transcription factor p45NF-E2 results in thrombocytopenia, impaired placental vascularization and intrauterine growth restriction (IUGR) in mice. The mechanism underlying the p45NF-E2-dependent placental defect and IUGR remains unknown. Here, we show that the placental defect and IUGR of p45NF-E2 (Nfe2) null mouse embryos is unrelated to thrombocytopenia, establish...

(5) For every real number r and for every subset P of E2 T such that P = {p; p ranges over points of E2 T: p1 ≥ r} holds P is closed. (6) For every real number r and for every subset P of E2 T such that P = {p; p ranges over points of E2 T: p1 ≤ r} holds P is closed. (7) For every real number r and for every subset P of E2 T such that P = {p; p ranges over points of E2 T: p1 = r} holds P is clo...

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Las plumas de pollo son residuos la industria avícola que se generan en grandes volúmenes, están conformadas por queratina, proteína rica cisteína, enlaces disulfuro y hidrofóbicos su reconversión es gran interés para diseñar biomateriales con aplicaciones ambientales. El objetivo generar esponjas queratina a partir aplicables el control derrames crudo, los cuales representan un importante daño...