During exponential growth some cells of E. coli undergo senescence mediated by asymmetric segregation of damaged components, particularly protein aggregates. We showed previously that functional cell division asymmetry in E. coli was responsive to the nutritional environment. Short term exposure as well as long term selection in low calorie environments led to greater cell division symmetry and...

Most therapeutic antibodies (Abs) target cell surface proteins on tumor and immune cells. Cloning of Ab gene libraries in E. coli and their display on bacteriophages is commonly used to select novel therapeutic Abs binding target antigens, either purified or expressed on cells. However, the sticky nature of bacteriophages renders phage display selections on cells challenging. We previously repo...

Household surveys are increasingly moving toward self-administered modes of data collection. To maintain a probability sample of the population, researchers must use probability methods to select adults within households. However, very little experimental methodological work has been conducted on within-household selection in mail surveys. In this study, we experimentally examine four methods—t...

Multilevel selection is a powerful theoretical framework for understanding how complex hierarchical systems evolve by iteratively adding control levels. Here I apply this framework to a major transition in human social evolution, from small-scale egalitarian groups to large-scale hierarchical societies such as states and empires. A major mathematical result in multilevel selection, the Price eq...

Within the learning framework of maximum weighted likelihood (MWL) proposed by Cheung, 2004 and 2005, this paper will develop a batch Rival Penalized Expectation-Maximization (RPEM) algorithm for density mixture clustering provided that all observations are available before the learning process. Compared to the adaptive RPEM algorithm in Cheung, 2004 and 2005, this batch RPEM need not assign th...

E-procurement has become an important function of enterprise information systems. The process of e-procurement includes the automatic definition of product requirements, search and selection for suppliers, negotiation and contracting with suppliers. However, the adoption of e-procurement encounters various exceptions from internal and external environments such as sharply increased demand, deli...

Landmark-based 3D hippocampal shape classification involves high-dimensional descriptor space, many noisy and redundant features, and a very small number of training samples. Feature selection becomes critical in this situation, because it not only improves classification performance, but also identifies the regions that contribute more to shape discrimination. This work identifies the drawback...

Some complete and some partial characterizations of continua are obtained in terms of the existence of an e-selection on one or another of their hyperspaces for each e > 0 .

The measurement of the single W production through the reaction e + e ? ! We e allows to measure the coupling between a photon and two W bosons. In this note we describe the selection of events of the We e type in e + e ? collisions at p s = 161 ? 172 GeV and derive a limit on the cross section, using only the hadronic decay channel of the W. From the cross section we derive limits on anomalous...

We apply a recently developed time-dependent Poisson random field model to aligned DNA sequences from two related biological species to estimate selection coefficients and divergence time. We use Markov chain Monte Carlo methods to estimate species divergence time and selection coefficients for each locus. The model assumes that the selective effects of non-synonymous mutations are normally dis...