This thesis work investigates the application of microfluidics to perform electrophysiological studies on cells, including investigations of the effect of cholesterol on the dynamic ion permeability of TRPV1 ion channels, and the application of a microfluidic device, the multifunctional pipette, in electrophysiological studies on brain slices. In the first part of this thesis, Chinese hamster o...

The No. 21 coal seam in the Zhengzhou mining area is a soft, three-layer, low-permeability prone to outbursts. three-layer structure includes and roof floor layers, which exhibit high gas contents poor permeability. dynamic hazards caused by outbursts are very serious. A new permeability-increasing fracturing technique that combines hydraulic perforation was developed specifically for geologic ...

The formation of large tin-tungsten (Sn-W) deposits around granitic intrusions requires the circulation volumes fluids within permeable structures. Half world’s tungsten production originates from highly mineralized veins above and altered part granite (the greisen), whose results intense fluid-rock interactions. During greisenization processes, mineral reactions involve a decrease in rock volu...

Some experimental results measuring P-wave phase velocity and seismic attenuation in laboratory under dry and water-saturated conditions at ultrasonic frequencies and atmospheric pressure on sandstone samples of the Milk River Formation in the Writingon-Stone Provincial Park (WOSPP), southern Alberta, are presented and are correlated with petrophysical data obtained from these samples as clay c...

Abstract: This paper presents the results of experimental determination of fiber bed permeability variation with porosity. Flow measurement experiments were designed to measure fiber mat permeability for fiber beds with various fiber volume fractions. Woven fiberglass, chopped fiberglass, and carbon fiber mats were used as reinforcements. The effects of reinforcement type and porosity on fiber ...

BACKGROUND The initial use of a 64-slice computed tomography (CT) scanner for obtaining quantitative perfusion data from a large ciliochoroidal melanoma, and correlation with 3T magnetic resonance imaging (MRI) dynamic enhancement and tumor histology. METHODS The CT perfusion scan was performed using 80 kVp, 250 mA and 1-sec rotation time for 40 sec. The analysis was performed using commercia...

OBJECTIVE To investigate microcirculatory differences between pathologic types of kidney tumor using 320-slice dynamic volume CT perfusion. METHODS Perfusion imaging with 320-slice dynamic volume CT was prospectively performed in 85 patients with pathologically proven clear cell renal cell carcinoma (RCC) (n = 66), papillary RCC (n = 7), chromophobe RCC (n = 5), angiomyolipoma (AML) with mini...

BACKGROUND AND PURPOSE It has been suggested that off-label use of transdermal nitroglycerine patches to prevent frostbite may lead to severe acute mountain sickness and ataxia. The aim of this study was to investigate the effect of nitroglycerine on brain vascular permeability by using dynamic contrast-enhanced MR imaging in a swine model. MATERIALS AND METHODS Eight Danish Landrace-Yorkshir...