Objective: The plant Ocimum basilicum belonging to family Lamiaceae is used in Skin disease, eye disease, fever and wounds. The present study was carried out to evaluate the effect of Ocimum basilicum whole plant (ethanolic and aqueous extract p.o.) on gastric and duodenal ulceration. Materials and Methods: The study was carried out on duodenal ulceration models such as cysteamine induced ulcer...

Background & Aims: Short-term follow-up studies show matically reduces ulcer relapse rates. The few studies lower relapse rates of duodenal and gastric ulcers after in patients with gastric ulcers had similar findings. successful Helicobacter pylori eradication. The aim of Only a few studies have followed up on patients with this study was to determine the long-term outcome duodenal ulcers for ...

Forty six patients with endoscopically diagnosed duodenal ulceration were randomly allocated to treatment with either sucralfate 1 g qds (n = 24) or cimetidine 200 mg tds and 400 mg nocte (n = 22). When the ulcers healed, a maintenance dose of sucralfate 1 g bd or cimetidine 400 mg nocte was given for one year (or until relapse if earlier). Biopsies of duodenal mucosa adjacent to ulcer sites fo...

changes observed on electron microscopy, and the mtDNA mutations. The electron microscopy study of peptic ulcer tissue showed swollen mitochondria and a loss of cristae within the mitochondrial cytoplasm. The mtDNA copy number of the peptic ulcer tissue samples was 2.5 times higher than that from the blood cells (2 180 547 vs 863 846 copies/ L). Proposed interactions among host, environment, an...

INTRODUCTION Bariatric procedures result in massive weight loss, however, not without side effects. Gastric acid is known to cause marginal ulcers, situated in the small bowel just distal to the upper anastomosis. We have used the wireless BRAVO™ system to study the buffering effect of the duodenal bulb in duodenal switch (DS), a procedure in which the gastric sleeve produces a substantial amou...

BACKGROUND Peptic ulcers were believed to be caused by stress, dietary factors, and gastric acid, but the link between H. pylori and peptic ulcers was identified in 1983. To see the frequency of Helicobacter pylori infection in patients with perforated duodenal ulcer and advise eradication therapy in these patients. This cross sectional study was conducted in Surgical Unit Hayatabad Medical Com...

It is not necessary here to consider the general subject of S^stric and duodenal ulceration, which for the most part lies Wlthin the domain of medicine rather than of surgery, although | need not remind this Society that these conditions no longer lr>terest the physician alone. Discussions which have taken P|ace within these walls have played no inconsiderable part in directing attention to the...

A survey of the smoking habits of 1217 outpatients undergoing upper gastrointestinal endoscopy was carried out over an 18 month period. Six hundred and twenty four were current smokers, 248 ex-smokers and 345 non-smokers. 11.9% of smokers had gastric ulcers, 7.7% of ex-smokers (p less than 0.025) and 4.6% of non-smokers (p less than 0.001). 2.8% of smokers had duodenal ulcers, 6.8% of ex-smoker...

Lysolecithin is formed when pancreatic juice and bile mix in the duodenum. Lysolecithin concentrations have been measured in intermittent samples of night gastric juice from patients with gastric ulcers and duodenal ulcers and in normal controls. In gastric ulcer patients, the mean of the peak concentrations (444 mug/ml) and mean of concentrations in all samples (199 mug/ml) were significantly ...

Background: Duodenal ulcers are mucosal erosions that penetrate into the muscularis propria of the duodenum. They are a result of an imbalance between aggressive and defensive factors. Various environmental factors like Helicobacter pylori infection, addictions to smoking and alcohol etc. and genetic factors have been reported to be associated with duodenal ulceration. Alpha-1-antitrypsin was s...