Background: Several studies have shown dissimilar results for the relationship between serum 25-hydroxyvitamin D concentration (25-OH-D) and disease activity in spondyloarthritis (SpA). Objectives: This study aims to assess whether vitamin levels vary according patients with SpA before after starting treatment biologic disease-modifying anti-rheumatic drugs (bDMARDs). Methods: An observational ...

As the world population continues to increase, with more than 50 percent of people now residing within cities, remaining natural and semi-natural habitats within urban areas play an increasingly important role for people and wildlife (Mortberg and Wallentinus, 2000; Benedict and McMahon, 2002; Jim, 2004; Town and Country Planning Association, 2004; Bierwagen, 2007; Gill et al., 2007; Tratalos e...

BACKGROUND Accumulating evidence demonstrates that the Urokinase Receptor (uPAR) regulates tumor cell migration through its assembly in composite regulatory units with transmembrane receptors, and uPAR88-92 is the minimal sequence required to induce cell motility through the Formyl Peptide Receptor type 1 (FPR1). Both uPAR and FPR1 are involved in melanoma tumor progression, suggesting that the...

peptic ulcer is one of the most prevalent gastrointestinal disorder, commonly occurs in developed countries. the present work was carried out to evaluate antiulcer effect of ipomoea batatas (l) dietary tuberous roots. the ethanolic extract of ipomoea batatas (eeib) was prepared by dynamic maceration for 7 days at room temperature using 70% ethanol (v/v). the antiulcer activity was evaluated by ...

objective(s): buthionine sulfoximine (bso) inhibits synthesis of glutathione as the main intracellular antioxidant. the aim of the present study is to investigate the effect of bso-induced oxidative stress on histological structure of testis, testosterone secretion and semen parameters. materials and methods: thirty male balb/c mice were divided into 3 groups. in control group, the mice did not...

BACKGROUND A putative tumor suppressor gene at chromosome 10p15, which contains KLF6 and other genes, is predicted to be lost during melanoma development, and its identity is unknown. In this study, we investigated the biological roles and identity of this tumor suppressor gene. METHODS The human UACC 903 melanoma cell line containing introduced DNA fragments from the 10p15 region with (10E6/...

BACKGROUND Medial patellofemoral ligament (MPFL) reconstruction is performed to prevent recurrent instability, but errors in femoral fixation can elevate graft tension. HYPOTHESIS Errors related to femoral fixation will overconstrain the patella and increase medial patellofemoral pressures. STUDY DESIGN Controlled laboratory study. METHODS Five knees with patellar instability were represe...