Dual-energy X-ray absorptiometry (DXA) is recognized as the reference method to measure bone mineral density (BMD) with acceptable accuracy errors and good precision and reproducibility. The World Health Organization (WHO) has established DXA as the best densitometric technique for assessing BMD in postmenopausal women and based the definitions of osteopenia and osteoporosis on its results. DXA...

characterized by low bone mass, bone deterioration, and decreased bone strength resulting in bone fragility and increased fracture risk.1 Osteoporosis increasingly is being recognized as an important cause of morbidity and mortality in older men. Approximately 2 million men in the United States have osteoporosis,2 and 1.5 million of these men are over the age of 65 years.3 The risk of osteoporo...

I. S. Masad, Y-M. Park, S-R. Lee, J. M. Wilson, P. C. Henning, B. H. Arjmandi, S. C. Grant, and J-S. Kim Department of Chemical & Biomedical Engineering, The Florida State University, Tallahassee, FL, United States, National High Magnetic field Laboratory, Tallahassee, FL, United States, Department of Nutrition, Food & Exercise Sciences, The Florida State University, Tallahassee, FL, United States

The strength of bone is related to its mass and geometry, but also to the physical properties of the tissue itself. Bone tissue is composed primarily of collagen and mineral, each of which changes with age, and each of which can be affected by pharmaceutical treatments designed to prevent or reverse the loss of bone. With age, there is a decrease in collagen content, which is associated with an...

Introduction: In patients with low initial bone mass, alendronate treatment causes small increases in DXA derived areal bone mineral density (BMD) and large decreases in fracture incidence. An increase in bone balance (the difference between bone formed and that resorbed per remodeling cycle) is often cited as the primary cause of increased BMD in clinical trials. Although some evidence exists ...

Methods 137 subjects aged 25 to 62 years were recruited across a range of BMI (17 to 50 kg/m) as part of a study examining the relationship between obesity and musculoskeletal health. Disabling foot pain was determined from the Manchester Foot Pain and Disability Index (MFPDI) and was defined as current foot pain and pain in the last month, as well as recording at least one disability item on t...

The purpose of this study was to compare the validity between three established prediction equations and our prediction equation referenced by DEXA (Dual-energy X-ray absorptiometry) on fat free mass (FFM) in Taiwan male soccer players. Methods: Twenty seven elite Taiwan soccer players were estimated by bioelectrical impedance analysis (BIA) and DEXA. The R2 value of FFM estimated by our predic...

Background No study has evaluated the potential independent and cumulative effects of physical activity, sedentary behavior, daily frequency of protein consumption, lean mass and muscular strength on mortality risk. Methods Data from the 1999-2002 NHANES were utilized (N = 1,079 adults 50-85 yr), with follow-up through 2011. Leg lean mass was estimated from DXA scans. Knee extensor strength w...

INTRODUCTION: The current benchmark for the assessment of fracture risk is the status of osteoporosis based on the measurement of bone mineral density (BMD) by dual-energy X-ray absorbtiometry (DXA). However, the ability of BMD to predict fracture occurrence has been shown to be limited, and over half of “osteoporotic fractures” occur among people who cannot be classified as having osteoporosis...