INTRODUCTION The application of deformable image registration (DIR) to megavoltage computed tomography (MVCT) images benefits adaptive radiotherapy. This study aims to quantify the accuracy of DIR for MVCT images when using different deformation methods assessed in a cubic phantom and nasopharyngeal carcinoma (NPC) patients. METHODS In the control studies, the DIR accuracy in air-tissue and t...

Riparin I is an alkamide with potential anxiolytic activity in preclinical studies. The characterization and understanding of solid-state properties play an importance role in drug development. For this work, the solid state of five riparin I batches (RIP-1, RIP-2, RIP-3, RIP-4, and RIP-5), obtained by the same synthesis process, were characterized by Scanning Electron Microscopy (SEM), Differe...

William Harvey Research Limited is the trading entity of the William Harvey Research Foundation a registered charity. Registered in England reg. no. 2437946. Chief Executive: Professor B.J.R. Whittle PhD, DSc Directors: Professor N. Benjamin FRCP DM, Dr J.A. Davies, Professor R.J. Flower DSc, Professor C. Thiemermann MD PhD and Professor D.A. Willoughby DSc FRCPath. WILLIAM HARVEY RESEARCH CONF...

Dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) is used to track the first pass of an exogenous, paramagnetic, nondiffusible contrast agent through brain tissue, and has emerged as a powerful tool in the characterization of brain tumor hemodynamics. DSC-MRI parameters can be helpful in many aspects, including tumor grading, prediction of treatment response, likelihood of ma...

BACKGROUND Decidua is in close contact with the fetal trophoblasts, and involved in immune relationship of mother to fetus. However, the roles of decidua and decidual stromal cells (DSC) in materno-fetal immune regulation remain to be elucidated. In the present study, the expression and regulation of chemokines and their receptors in decidua and DSCs were investigated. METHODS AND RESULTS The...

This paper presents an artificial-neural-network-based direct-self-control (ANN–DSC) scheme for an inverter-fed three-phase induction motor. In order to cope with the complex calculations required in direct self control (DSC), the proposed artificial-neural-network (ANN) system employs the individual training strategy with fixed-weight and supervised models. A computer simulation program is dev...

BACKGROUND AND PURPOSE Perfusion measurement in multiple sclerosis (MS) may cast light on the disease pathogenesis and lesion development since vascular pathology is frequently demonstrated in the disease. This study was performed to investigate the perfusion characteristics in MS lesions using dynamic susceptibility contrast MR imaging (DSC-MRI) to better understand the hemodynamic changes in ...

During visual fixation, the image of an object is maintained within the fovea. Previous studies have shown that such maintenance involves the deep superior colliculus (dSC). However, the mechanisms by which the dSC supports visual fixation remain controversial. According to one view, activity in the rostral dSC maintains gaze direction by preventing neurons in the caudal dSC from issuing saccad...

BACKGROUND AND PURPOSE The purpose of this study was to evaluate the potential clinical value of arterial spin-labeled (ASL) perfusion MRI in acute ischemic stroke (AIS) through comparison with dynamic susceptibility contrast (DSC) enhanced perfusion MRI. METHODS Pseudocontinuous ASL with 3-dimensional background-suppressed gradient and spin echo readout was applied with DSC perfusion MRI on ...