conclusions multiple prescription drug abuse and salt/salty food addiction usually reflects a personality of addiction, which leads to harmful use and dependence. case presentation a 28-year-old woman presented with tetany due to hypocalcemia, hypokalemia and hypomagnesemia. she had a history of laxative and diuretic abuse, and salt craving. psychiatric evaluation revealed a disturbed social hi...

BACKGROUND Medication policy development in Thailand is continually promoting rational drug use. Letrozole, an endocrine therapy drug, is usually prescribed for post-menopausal status early and advanced stage breast cancer. After Ministry of Public Health announced Letrozole as compulsory licensed drug in 2009, more breast cancer patients can access to this drug at low cost especially those wit...

Instructional policy reforms that focus on standards and assessments have gained popularity in the last two decades. State governments, which had previously left most instructional matters to local governance, set challenging learning standards and developed related assessments and curricular frameworks. Despite their popularity and persistence, standards-based reforms face the challenge of suc...

BACKGROUND Biobanks increasingly presume long-term storage of biomaterials and data that shall be used for future research projects which are today unspecified. Appropriate consent documents for sample donors must therefore explain the breadth of consent and other elements of the biobank governance framework. Recent reviews demonstrated high variability in what issues these documents mention or...

Thirty eight assessments of postmicturition residual volume were undertaken in 34 babies of various gestational and postnatal ages using abdominal ultrasonography. Twenty one (54%) babies had no detectable residual bladder volume. In all cases manual expression of the bladder failed to eliminate the residual volume. The formula widely used in the estimation of fetal bladder size and urine outpu...

Background: Chronic opioid use is a major public health problem with significant morbidity. The aim of this study was to investigate factors associated with sustained remission among a sample of Iranian chronic opioid users in Shiraz, Iran.Methods: This was a cross-sectional study to evaluate sustained remission among chronic opiate users aged 20-60 years. Participants included two groups: 365 ...

background the goal of the present study was the preparation and evaluation of griseofulvin topical gel as a drug dosage form with appropriate efficacy and stability. material and methods to select the best formulation, formulations with different concentration of carbomer and hpmc were evaluated for their appearance. then evaluated for physicochemical characteristics such as rheologic behavior...

Zebrafish represent a vertebrate model organism that has been widely, and increasingly, employed over the last decade in the study of developmental processes, wound healing, microbe-host interactions, and drug screening. With the increase in the laboratory use of zebrafish, several advantages, such as a high genetic homology to humans and transparent embryos, which allow clear disease evaluatio...