Objective: The present research work was carried out to prepare Ketorolac printed Oral Thin Films using a pneumatic pressure printer. In this research, we attempted non-contact printing system by pressure-based printer that incorporates of active pharmaceutical ingredients onto medical-grade Orodispersible film for developing personalized medication. Methods: the Trometamol used as model drug. ...

The main objective of this paper was to manipulate the Nano Fibrous Scaffold "NFS" surface roughness to achieve a new transdermal drug release profile. To assess the intrinsic mechanical properties of Nylon 6 or polycaprolactam, such as its proper resiliency, it was considered as the matrix. Cetirizine was used as a drug model and was loaded (1% w/v) to polymer solution (30%w/v) before spinning...

The main objective of this paper was to manipulate the Nano Fibrous Scaffold "NFS" surface roughness to achieve a new transdermal drug release profile. To assess the intrinsic mechanical properties of Nylon 6 or polycaprolactam, such as its proper resiliency, it was considered as the matrix. Cetirizine was used as a drug model and was loaded (1% w/v) to polymer solution (30%w/v) before spinning...

Transdermal delivery of ondansetron hydrochloride is one of the promising ways to maximize the therapy in contrast to oral delivery. Current investigation efforts are focused in formulating the ondansetron hydrochloride matrix-type transdermal film by incorporating hydrophilic and hydrophobic polymers. In this study, ondansetron hydrochloride transdermal films were prepared using solvent evapor...

OBJECTIVE The aim of this study was to evaluate the bioequivalence of two drug products, generic clopidogrel bisulfate 75 mg film-coated tablets versus the reference Plavix(®) clopidogrel bisulfate 75 mg film-coated tablets. METHODS Bioequivalence of tablets was tested by comparisons against the reference brand product in accordance with the requirements of the Declaration of Helsinki, the cu...

Mucoadhesive buccal film is developed as a promising dosage form, which has prominent advantages because of drug delivery through buccal mucosa. New formulation of buccal films containing rizatriptan benzoate (RB) was prepared by solvent casting method using various concentrations of hydroxypropyl methylcellulose (HPMC K4M), polyvinyl alcohol (PVA), polyethylene oxide (PEO), glycerol, stevia, a...

in this research, the mechanical properties of seven types of nanofilm with differing amounts of silver and silver-clay particles were studied. the elasticity of modulus, tensile strength, toughness, elongation at break, tear strength and color of nanofilms were compared with those of ordinary ldpe film. results showed that the inclusion of nano particles increased the modulus of elasticity, te...

Nabumetone is the effective drug for the treatment of reumatoid arthritis and osteoarthritis. The drug has a half life of 23 hrs and its oral bioavailability is only 30%. The aim of the study is to prepare 6 formulations of liposomal carrier for Nabumetone for the treatment of arthritis that is capable of delivering the drug to the specific target site by topical route by using different ratios...