the overall incidence of glucose-6-phosphate dehydrogenase (g6pd) deficiency in iranian population is estimated around 10%-14.9% . g6pd deficiency is an x-linked disorder and 80% of donors are usually male. at present, donors’ blood is not routinely screened for g6pd deficiency in iran blood bank where for detecting such enzyme deficiency, reliance is placed on pre-donation data. thus, the g6pd...

Method A total of 16 patients with clinically well-established maculopapular exanthema due to antiepileptic drugs hypersensitivity in remission state and 15 drug-exposed control donors without DHR were included to the study. Peripheral blood mononuclear cells of investigated individuals were isolated and cultured under defined conditions with drugs. IFN-gamma production was measured with electr...

The 2008 Guidelines for Gamete and Embryo Donation provide the latest recommendations for evaluation of potential sperm, oocyte, and embryo donors, incorporating recent information about optimal screening and testing for sexually transmitted infections (STIs), genetic diseases, and psychological assessments. This revised document incorporates recent information from the U.S. Centers for Disease...

The influence of simple molecular descriptors on the melting point temperature (Tm) has been investigated using a matched molecular pair (MMP) analysis. This method has been used to identify small structural differences between pairs of molecules, which are related to changes in Tm. Our analysis shows that the number of hydrogen bond donors, hydrogen bond acceptors and rotatable bonds has a sig...

The prevalence of hepatitis A virus antibodies was tested by radioimmunoassay in Norway in healthy blood donors, in patients without clinical signs of liver diseases and in two selected groups of patients. The presence of hepatitis A antibodies was highly age-dependent in 625 normal persons. A major reduction occurred from 50 per cent or more in those born before 1938 to 10 per cent or less amo...

Background:Nowadays, one of the main challenges of the blood transfusion organization is the procurement, distribution, and monitoring of the appropriate use of blood and its products. Therefore, the aim of this study was to investigate the prevalence of Transfusion Transmitted Infections (TTIs) including human immunodeficiency virus (HIV+), hepatitis B virus (HBV+), and hepati...