parapharyngeal abscess is a life-threatening disease. upper respiratory tract infection is the main cause in children. we present a 15-month-old boy admitted to the emergency ward with the chief complaint of difficulty in breathing caused by parapharyngealabscess. his condition deteriorated gradually, and he transferred to the operation theater quickly for abscess drainage and because of the di...

To cite: Parkinson MH, Patel R, Davagnanam I, et al. Pract Neurol 2014;14: 409–414. A 26-year-old woman presented after developing slurred speech and drooling overnight. She had a 6-month history of tiredness and poor concentration, and episodes of loss of consciousness accompanied by paraesthesia of her hands, feet and mouth. Occasionally, one arm would ‘hang in a strange way’. Her mother repo...

A very significant challenge in Alzheimer's disease today is the discovery of suitable technologies for detection of the disease that are easy to use, cost effective and non-invasive. In this study we demonstrate that saliva biomarkers are a suitable option for detection of the disease. Accordingly, we collected saliva samples by three different methods from age and gender matched Alzheimer's p...

Background. Angelman syndrome (AS) is a genetic disease whose incidence varies from one in 10.000 to one in 40.000 newborns. Clinically, it is characterized by a severe growth delay, speech alterations, ataxia, craniofacial abnormalities and strange behaviors. The aim of this paper is to provide a systematic review of the literature regarding the oral manifestations of this uncommon disease. Ma...

Among the next generation of antipsychotics, aripiprazole is the molecule, which has been defined to have a special mode of action, which is the stabilization of the dopamine system. Different studies have found the incidence of extrapyramidal symptoms (EPS) with this antipsychotic to be very much insignificant. Studies done so far have reported the incidence of extrapyramidal side effects to b...

Caring for children and adolescents with developmental disabilities is challenging because of their susceptibility to varying degrees of respiratory morbidity and mortality. This article discusses the common pulmonary problems affecting children with developmental disabilities. Topics to be discussed include gastroesophageal reflux, drooling, and dysphagia and their relation to aspiration and a...

CASE A nine-month-old girl was brought to the emergency department because of right neck swelling. She had recently been discharged from the same hospital after a brief admission for pneumonia that had followed influenza. The mother denied noticing increased drooling, dyspnea, or stridor. Pooled oral secretions were present on physical exam, but the patient was calm with normal vital signs (Fig...