BACKGROUND There are no studies on cross-reactivity of betalactams among patients allergic to penicillin, or on the negative predictive value (NPV) of penicillin allergy evaluation from Arabian Gulf countries. OBJECTIVE We aimed to assess the role and NPV of drug provocation test (DPT) for betalactam hypersensitivity reactions in patients referred for allergy evaluation in Kuwait. METHODS S...

BACKGROUND In Pakistan, only 59-73% of children 12-23 months of age are fully immunized. This randomized, controlled trial was conducted to assess the impact of a low-literacy immunization promotion educational intervention for mothers living in low-income communities of Karachi on infant immunization completion rates. METHODS Three hundred and sixty-six mother-infant pairs, with infants aged...

Several studies have shown that the presence of IgE antibodies to house dust mites (HDM), particularly Dermatophagoides pteronyssinus (Dpt), is an important risk factor for asthma. Allergen immunotherapy is indicated for patients with IgE antibodies to clinically relevant allergens. The aims of this study were to analyze the levels of specific serum IgE to Der p 1 and Der p 2 allergens in mite-...

A combined experimental and theoretical approach has been used to investigate the redox properties of two dinuclear Ru(II) complexes, 2a and 2b, containing the planar dpt-ph-dpt bridging ligand (dpt-ph-dpt = 1'',4''-bis(2,4-dipyrid-2'-yl-1,3,5-triazin-6-yl)benzene). The redox properties of the free bridging ligand and the X-ray structure of 2a have also been reported, together with the X-ray st...

Thermodynamic conventions suffer from describing dynamical distinctions, especially when the structural and energetic changes induced by rare events are insignificant. By using ensemble theory in trajectory space, we present a statistical approach to address this problem. Rather than spatial particle-particle interaction which dominates thermodynamics, temporal correlation of dynamics. The zero...