Aqueous extract of a natural herb, Terminalia chebula was tested for potential antioxidant activity by examining its ability to inhibit γ-radiation induced lipid peroxidation in rat liver microsomes and damage to superoxide dismutase (SOD) enzyme in rat liver mitochondria. HPLC analysis of the extract showed the presence of compounds such as ascorbate, gallic acid and ellagic acid. This was als...

BACKGROUND Launaea procumbens (LP) has been used as a food supplement in Pakistan. In this study methanolic crude extract (LPME) of the whole plant and its different fractions; n-hexane (LPHE); ethyl acetate (LPEE) and chloroform (LPCE) were studied for the determination of total flavonoid and phenolics contents along with multifaceted in vitro scavenging assays. RESULTS Considerable amount o...

A new acylated flavonol glycoside, namely gomphrenol-3-O-(5'''-O-E-feruloyl)-β-D-apiofuranosyl(1→2)[β-D-glucopyranosyl-(1→6)]-β-D-glucopyranoside (1) was isolated from the aerial parts of Chenopodium foliosum Asch. The structure of 1 was determined by means of spectroscopic methods (1D and 2D NMR, UV, IR, and HRESIMS). Radical scavenging and antioxidant activities of 1 were established using DP...

This paper presents the design of some novel 3-acetylcoumarin derivatives, based on minimal inhibitory concentration values (MICs) previously obtained against some microorganism cultures, Gram positive and negative bacteria and fungi. Some of these molecules exhibited antibacterial activity against S. aureus, comparable to that of the standard used (impinem). The in vitro antioxidant activities...

To determine the significance of germination on phytochemical constituents and non-enzymatic antioxidant activities of Ceiba pentandra seed extracts. Phytochemicals and antioxidant activities of raw and germinating seeds of Ceiba pentandra were estimated by different methods. The levels of phytochemical constituents were influenced by germination and increased except alkaloids and tannins, whic...

The DPPH radical scavenging activity of 2',4',6'-trihydroxy- and 2'-hydroxy-4',6'-dimethoxychalcones carrying a 2,3- and 3,4-dihydroxylated, and 3,4,5-trihydroxylated B-ring was evaluated in alcoholic and non-alcoholic solvents. All test compounds scavenged more than two equivalent of radicals by a possible conversion to the corresponding B-ring quinones and in most cases subsequently underwent...

BACKGROUND Bitter cumin (Centratherum anthelminticum (L.) Kuntze), is a medicinally important plant. Earlier, we have reported phenolic compounds, antioxidant, and anti-hyperglycemic, antimicrobial activity of bitter cumin. In this study we have further characterized the antioxidative activity of bitter cumin extracts in various in vitro models. METHODS Bitter cumin seeds were extracted with ...

Whole grain foods have been recommended for healthy diets as being recognized sources of dietary fiber and antioxidants. A diverse array of wheat was evaluated in terms of bioactive compounds and antioxidant capacity. The bioactive compounds examined include phenolic acids, carotenoids and tocols which were determined by HPLC. Antioxidant was based on the determination of scavenging capacity of...

Only a few species of the large Astragalus genus, widely used for medicinal purposes, have been thoroughly studied for phytochemical composition. The aim of our research was to investigate the rarely studied species A. glycyphyllos L. and A. cicer L. for the distribution of mineral elements and phytochemicals in whole plants at two growth stages and in morphological fractions. We also investiga...

UNLABELLED Crataegus succulenta Schrad. ex Link is widely spread in North America. A literature survey revealed no studies on the chemical composition and biological effects of this species. AIM The aim of the present study was to investigate the phenolic content, free radical scavenging and 15-lipoxygenase inhibitory effects of Crataegus succulenta leaf and flower extracts. MATERIAL AND ME...