Progressive supranuclear palsy (PSP) with predominant cerebellar ataxia (PSP-C) is a rare phenotype of PSP. The clinical and radiological features of this disorder remain poorly characterized. Through a retrospective case series, we aim to characterize the clinical and radiological features of PSP-C. Four patients with PSP-C were identified: patients who presented with prominent cerebellar dysf...

We report a 37-year-old woman with Niemann-Pick disease type C (NPC) 1. At the age of 8 years, she presented slow running followed by both fingers dystonia at the age of 10 years. At the age of 16 years, she developed declined scholastic achievement. On her first visit at the age of 17 years, she showed dystonia, ataxic gait and vertical supranuclear gaze palsy. We suspected it was NPC. She pre...

This study examined the role of eccentric gaze dynamics in the generation of visual illusions of self-motion (i.e., vection). In Experiment 1, observers maintained their gaze either upward, downward, leftward, or rightward with respect to the center of a radially expanding optic flow pattern, which simulated forward self-motion in depth through a 3D cloud of objects. Real-time vection strength ...

OBJECTIVES To investigate whether ocular torsion and vertical misalignment differ in the upright vs supine position in skew deviation and to compare these findings with those in trochlear nerve palsy. METHODS Ten patients with skew deviation, 14 patients with unilateral peripheral trochlear nerve palsy, and 12 healthy subjects were prospectively recruited. With subjects first in the upright p...

Clinical Features of Progressive Supranuclear Palsy Progressive supranuclear palsy (PSP) is a neurodegenerative disorder characterised by parkinsonism, supranuclear ophthalmoplegia, dysphagia and cognitive dysfunction. The National Institute of Neurological Disorders and Stroke (NINDS) PSP criteria are widely used for clinical diagnosis. However, the clinical phenotypes of pathologically confir...

PURPOSE Surgical management of superior oblique palsy (SOP) is challenging because of combined vertical, horizontal, and torsional misalignment. The authors report the surgical results of patients with large primary position hypertropias (> 20 prism diopters [PD]) due to unilateral SOP. METHODS Criteria for success included correction of the anomalous head posture, primary position alignment ...

Fig 1: Midsagittal section through brainstem showing prominent midbrain atrophy without pontine atrophy resembling a hummingbird (arrow showing the beak) and a penguin Fig 2: Axial MRI showing selective atrophy of the midbrain tegmentum, with relative preservation of the tectum and cerebral peduncles resembling Mickeymouse (Arrow) A fifty year old male was brought by his wife with insidious ons...

BACKGROUND Few cases of frontotemporal dementia parkinsonism (FTDP-17) have been described in the literature. To our knowledge, this is the first Italian case. OBJECTIVE To report a case of FTDP linked to chromosome 17, exhibiting progressive supranuclear palsy on initial examination. PATIENT A 50-year-old woman had a 4-year history of behavior changes associated with slowly progressive men...

Research & Development in Material Science Downward Vertical Continuous Casting of Industrial Lead Zakaria Boumerzoug*, Nahala Soundsous Boutaba and Khawla Helis Mechanical Engineering Department, University Biskra, Algeria *Corresponding author:Zakaria Boumerzoug, Submission: July 12, 2023;Published: 19, 2023 DOI: 10.31031/RDMS.2023.19.000957 ISSN: 2576-8840 Volume 19 Issue 2