Intercellular junctions are crucial for mechanotransduction, but whether tight junctions contribute to the regulation of cell-cell tension and adherens junctions is unknown. Here, we demonstrate that the tight junction protein ZO-1 regulates tension acting on VE-cadherin-based adherens junctions, cell migration, and barrier formation of primary endothelial cells, as well as angiogenesis in vitr...

Pneumocephalus is commonly seen after craniofacial injury. The pathogenesis of pneumocephalus has been debated as to whether it was caused by ball valve effect or combined episodic increased pressure within the nasopharynx on coughing. Discontinuous exchange of air and cerebrospinal fluid due to "inverted bottle" effect is assumed to be the cause of it. Delayed tension pneumocephalus is not com...

The importance of surface tension effects is being recognized in the context of soft composite solids, where they are found to significantly affect the mechanical properties, such as the elastic response to an external stress. It has recently been discovered that Eshelby's inclusion theory breaks down when the inclusion size approaches the elastocapillary length L≡γ/E, where γ is the inclusion/...

Background. Tension pneumothorax can infrequently cause ventricular arrhythmias and increase the threshold of defibrillation. It should be suspected whenever there is difficulty in defibrillation for a ventricular arrhythmia. Purpose. To report a case of traumatic tension pneumothorax leading to ventricular tachycardia and causing defibrillator failure. Case. A 65-year-old African-American fema...

With the aid of brownian dynamics models, it is possible to estimate polymer tension by monitoring polymers' transverse thermal fluctuations. To assess the precision of the approach, brownian dynamics-based tension estimates were compared with the force applied to rhodamine-phalloidin labeled actin filaments bound to polymer beads and suspended between two optical traps. The transverse thermal ...

The spatial string tension, a classic non-perturbative probe for the convergence of the weak-coupling expansion at high temperatures, can be determined in full QCD as well as in a dimensionally reduced effective theory. Comparing both approaches, we find surprisingly good agreement almost down to the critical temperature of the deconfinement phase transition. c Copyright owned by the author(s) ...

Article history: Received 30.08.2013. Received in revised form 04.12.2013. Accepted 12.12.2013. Filament winding products are widely used due to their quality, high strength and a series of advantages in the industrial areas. The process involves winding filaments under varying amounts of tension over a male mould or mandrel. The tension control product has become the most important object in t...

[1] The development of transient thermal stress in suboceanic mantle is investigated on the basis of two-dimensional thermoviscoelastic models incorporating composite rheology appropriate for dry oceanic lithosphere. Thermal stress is shown to be sufficiently high to deeply fracture the coldest part of lithosphere, e.g., to the depth of at least 30 km (and possibly down to 50 km) in 100-Ma-old ...

Abstract In this study, the dynamics of tendon/top tension riser (TTR) system a tension-leg platform (TLP) are investigated through an experiment and by using absolute nodal coordinate formulation (ANCF). First, model test TLP is conducted in water tank Harbin Engineering University to examine motion response dynamic characteristics tendon TTR. The scale ratio set 1: 66.3. Then, on basis ANCF, ...

Instabilities of a thin viscous film flowing down a uniformly heated plane are investigated in this study. The heating generates a surface tension gradient that induces thermocapillary stresses on the free surface. Thus, the film is not only influenced by gravity and mean surface tension but also the thermocapillary force is acting on the free surface. Moreover, the heat transfer at the free su...