Abstract Background After myocardial infarction (MI), inflammation and its resolution modulate the extent of damage. 68Ga-DOTATATE is a PET tracer that binds to somatostatin receptor 2 (SST2), which up-regulated in pro-inflammatory macrophages [1]. Purpose We investigated PET/MRI for quantifying post-infarct inflammation. Methods In this prospective observational cohort study, participants with...

T hrough its Priority Review mechanism, the U.S. Food and Drug Administration (FDA) recently approved 2 radiopharmaceutical products for use as diagnostic PET agents. The first, approved on May 27, was Axumin (18F-fluciclovine) injection, indicated for use in PET imaging to identify suspected sites of prostate cancer recurrence in men with elevated levels of prostate-specific antigen (PSA) foll...

1. Gla ser B, Landau H, Smilovici A, Nesher R. Persistent hyperinsulinaemic hypoglycaemia of infancy: Long-term treatment with the somatostatin analogue Sandostatin. Clin Endocrinol (Oxf) 1989;31:71-80. 2. Prashanth GP, Kurbet SB. Comment on persistent hyperinsulinemic hypoglycemia of infancy. J Indian Assoc Pediatr Surg 2013;18:92. 3. James C, Kapoor RR, Ismail D, Hussain K. The genetic basis ...

This manuscript reports on a patient with a metastatic gastrointestinal stromal tumor (GIST) refractory to standard first-line treatment, who underwent a gallium-68 scan based on pre-clinical data of somatostatin receptor (SSTR) expression in such tumors. The gallium-68 DOTATATE scan determined significant somatostatin receptor avidity as hypothesized, suggesting that this imaging modality may ...

We report a rare case of a laparoscopic splenectomy performed for a carcinoid metastasis. The patient represented with pleuritic left-sided chest pain from pleural deposits 9 years following resection of a primary lung carcinoid tumour. They were found to have a 4.7 cm splenic lesion on CT with a probable left acetabular metastasis demonstrated on Gallium PET scan. The patient underwent laparos...