Rheumatoid arthritis (RA) is one of the most common autoimmune diseases, affecting 0.5% to 1% population. It could ultimately result in joint destruction, functional decline, work disability, and enhanced mortality. Cyclic citrullinated peptide antibodies (CCP Abs) are useful biomarkers for early detection diagnosis RA. In this study, we used plant viral-based expression vectors that produce ra...

Using genetic immunisation of mice, we produced antibodies against chicken interleukin-12p40 (chIL-12p40), also known as IL-12β. After a final injection with a recombinant chIL-12p40 protein, several stable hybridoma cell lines were established which secreted monoclonal antibodies (mAbs) to this component of the heterodimeric IL-12 cytokine. Specific binding of three of the mAbs to COS-7 cell-d...

Lactoferrin (LF) has antimicrobial properties against bacteria, fungi and several viruses including herpes virus, HIV and hepatitis C virus. The aim of this study was to detect LF in PMNs and plasma of the patients suffering from hepatitis C and the healthy persons. The sonicated solutions of PMNs of two groups were evaluated by SDS-PAGE (10%), isoelectric focusing (30%) and dot blotting. The l...

Expression profiling on a large scale, as is the case in drug discovery, is often accomplished through use of sophisticated solid-phase protein microarrays or multiplex bead technologies. While offering both high-throughput and high-content analysis, these platforms are often too cost prohibitive or technically challenging for many research settings. Capitalizing on the favorable attributes of ...

Bertino, Ferrari and Atluri (BFA) have recently presented a model for specifying and enforcing authorization constraints for Workflow Management Systems (WFMS). The model is comprehensive and exhibits strong properties such as (1) a language to express constraints, (2) formal notions of constraint consistency and (3) algorithms for role-task and user-task assignments. In this paper, we extend t...

Recently, IACR ePrint archive posted two fully homomorphic encryption schemes without bootstrapping. In this note, we show that these schemes are trivially insecure. Furthermore, we also show that the encryption schemes of Liu and Wang [6] in CCS 2012 and the encryption scheme of Liu, Bertino, and Xun [5] in ASIACCS 2014 are insecure either.