BACKGROUND The purpose of this study was to assess the dosimetric and clinical feasibility of volumetric modulated arc based hypofractionated stereotactic radiotherapy (RapidArc) treatment for large acoustic schwannoma (AS>10 cc). MATERIALS AND METHODS Ten AS patients were immobilized using BrainLab mask. They were subject to multimodality imaging (magnetic resonance and computed tomography) ...

Background: Some ssues in human body are radiobiologically different from water and these inhomogeneity must be considered in dose calcula on in order to achieve an accurate dose delivery. Dose verifica on in complex radia on therapy techniques, such as intensity‐modulated radia on therapy (IMRT) calls for volumetric, ssue equivalent and energy independent dosimeter. The purpose of this study i...

Techniques for high precision irradiation experiments with protons, to investigate the volume dependence of the tolerance dose of the rat cervical spinal cord are described. In the present study, 50% of the lateral cross section of the spinal cord was irradiated. The diameter of the cross section of this part of the rat spinal cord is at maximum 3.5 mm. Therefore, a dedicated procedure was deve...

BACKGROUND To compare volumetric-modulated arc therapy plans with conventional radiation therapy (3D-CRT) plans in pancreatic and bile duct cancers, especially for bilateral kidney preservation. METHODS A dosimetric analysis was performed in 21 patients who had undergone radiotherapy for pancreatic or bile duct carcinoma at our institution. We compared 4-field 3D-CRT and 2 arcs RapidArc (RA) ...

The purpose of this investigation was to evaluate the potential dosimetric benefits of a two-phase adaptive intensity-modulated radiotherapy (IMRT) protocol for patients with locally advanced nasopharyngeal cancer (NPC). A total of 17 patients with locally advanced NPC treated with IMRT had a second computed tomography (CT) scan after 17 fractions in order to apply and continue the treatment wi...

BACKGROUND Current therapeutic standard for locally advanced rectal cancer is the neoadjuvant radiochemotherapy with total mesorectal excision. Diarrhoea is the main acute side effect, induced by the dose to the small-bowel, frequently leading to a treatment modification. Aim of this study was to analyse the differences between the irradiated small-bowel volumes and the occurrence of acute diar...

PURPOSE To investigate dosimetric effects of bladder distention on organs at risk (OARs) during treatment of endometrial cancer using 3D image-based planning of postoperative vaginal vault brachytherapy (BRT). MATERIAL AND METHODS Fifteen patients with early-stage endometrial cancer were studied, each undergoing adjuvant BRT of vaginal vault via 3.5 cm diameter cylinder. As treatment, 25 Gy i...

Background . Radiation therapy for high-risk prostate cancer presents a challenge radiotherapists. The improvement of treatment outcomes is associated with radiation dose escalation and prophylactic irradiation lymph nodes, therefore, the development new schemes needed. Simultaneous integrated boost technique based on volumetric modulated arc most efficient option. Material Methods anatomical d...

background: inclusion of inhomogeneity corrections in intensity modulated small fields always makes conformal irradiation of lung tumor very complicated in accurate dose delivery. objective: in the present study, the performance of five algorithms via monte carlo, pencil beam, convolution, fast superposition and superposition were evaluated in lung cancer intensity modulated radiotherapy planni...

Purpose: The work aims at studying forty Intensity-modulated radiation therapy (IMRT) plans designed using KonRad system and evaluating each of them under different conditions to study the effect of beams' orientations on the plan quality. Methods: Clinical step-and-shoot IMRT treatment plans were designed for twenty patients, suffering from different types of non-CNS solid tumors, to be delive...