نتایج جستجو برای: dopaminergic system
تعداد نتایج: 2245586 فیلتر نتایج به سال:
The role of dopaminergic imaging in patients with symptoms of dopaminergic system neurodegeneration.
Diagnosis of neurological and psychiatric conditions associated with disturbances of dopaminergic functioning can be challenging, especially in the early stages, and may be assisted with biomarkers such as dopamine system imaging. Distinguishing between Alzheimer's disease and dementia with Lewy bodies is a major diagnostic challenge. Clinical diagnosis of Parkinson's disease is straightforward...
Impulsive-compulsive disorders such as pathological gambling, hypersexuality, compulsive eating, and shopping are side effects of the dopaminergic therapy for Parkinson's disease. With a lower prevalence, these disorders also appear in the general population. Research in the last few years has discovered that these pathological behaviors share features similar to those of substance use disorder...
Dopamine dysregulation syndrome is a complication of the dopaminergic treatment for Parkinson's disease, probably related to sensitization of the mesolimbic dopamine system. The relationship between dopamine dysregulation syndrome and deep brain stimulation of the subthalamic nucleus remains unclear. We report three patients with Parkinson's disease who developed de novo dopamine dysregulation ...
Enhanced locomotion in a habituated environment is a well documented effect of nicotine mediated by the mesotelencephalic dopaminergic system. The nicotinic receptor subunit alpha6 is, among other subunits, strongly expressed in the dopaminergic neurons of the mesencephalon. To examine the functional role of this subunit, we inhibited its expression in vivo using antisense oligonucleotides. In ...
Inflammatory processes described in Parkinson's disease (PD) and its animal models appear to be important in the progression of the pathogenesis, or even a triggering factor. Here we review that peripheral inflammation enhances the degeneration of the nigrostriatal dopaminergic system induced by different insults; different peripheral inflammations have been used, such as IL-1β and the ulcerati...
introduction: nigrothalamocortical tract is one of the main outputs of the basal nuclei, but its role in motor disturbances is vauge, because there is little informations on its connection structure. some electrophysiological and pharmacological surveys report that none-dopaminergic outputs originate from reticular part of substantia nigra and end at thalamus. in this study the topographical co...
چکیده : نظام انتخاباتی قواعد و چار چوب های به رسمیت شناخته شده ای است که بیانگر چگونگی تبدیل آرای مردم به مناصب و پست های سیاسی است. این نظام انتخابات باید به گونه ای عمل کند که نتیجه آن فراهم شدن مکانیسم و ساز و کار مطلوب و مناسب برای برگزاری انتخابات سالم و رقابتی باشد. به نظر می رسد نظام انتخاباتی جمهوری اسلامی ایران دارای ضعف ها و نواقصی است که به سبب آن ها نمی توان انتخابات مطلوب را برگزا...
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