Clustered regularly interspaced short palindromic repeats/CRISPR associated nuclease 9 (CRISPR-Cas9) system was instigated first into eukaryotes in the last ten years are becoming productive and worldwide application for genome modification. Genome engineering through insertion of foreign DNA insert have numerous disadvantages which could be overcome by use DNA-free editing. Various ways editin...

It is my pleasure to introduce the second issue of Bioengineering and Translational Medicine during its inaugural year. This issue focuses on one of the most pressing questions for drug delivery scientists today: How can we engineer systems that protect the sensitive cargo that is DNA and RNA while simultaneously facilitating intracellular delivery? With continuous advances in our understanding...