We consider two models of interacting DNA molecules: First is (four parametric) bubble coalescence model in DNAs (shortly: BCI-DNA). Second (three a condensed molecules (shortly BCC-DNA). To study thermodynamics BCI-DNA and BCC-DNA we use methods statistical physics. Namely, define Hamiltonian each give their translation-invariant Gibbs measures (TIGMs). For the first model, find parameters suc...

The i-motif DNA, also known as i-DNA, is a non-canonical DNA secondary structure formed by cytosine-rich sequences, consisting of two intercalated parallel-stranded duplexes held together hemi-protonated cytosine–cytosine+ (C:C+) base pairs. growing interest in the i-DNA target anticancer therapy increases need for tools rapid and meaningful interpretation spectroscopic data samples. Herein, we...

conclusions it seems that smoking cannot increase the prevalence of high risk hpv 16, 18 in saliva samples. results there were no high-risk types of virus in patients and no significant differences between the groups (p = 1). patients and methods a hundred healthy adult subjects were selected from zahedan dental school for this pilot study. dna was isolated from saliva samples and screened for ...

background: induction chemotherapy for acute lymphoblastic leukemia achieves complete remis sion in over 90% of children. it is apparent therefore that many patients in clinical remission and with out residual disease detectable by conventional light microscopy of peripheral blood or bone marrow films still harbor viable cells of the original disease mrd analysis does have a useful role to play...

the rapidly expanding fields of pharmacogenomics and pharmacodiagnostics have presented the pathology laboratories with many challenges and opportunities. as custodians of patient tissues, these laboratories are in the logical position to perform biomolecular testing for proper management of patients. in order to meet these challenges, the pathology laboratories of the twenty-first century shou...