To investigate whether microvolumes (< or = 10 microliters) of nicotinic, muscarinic, and beta-adrenergic agonists can modify intrinsic cardiac neuronal activity, nicotine, 1,1-dimethyl-4-phenylpiperazinium iodide (DMPP), bethanechol chloride, and isoproterenol were separately administered adjacent to spontaneously active in situ epicardial neurons in 15 anesthetized dogs. Neuronal activity gen...

Japan. Abstract-Secretory and vascular responses to various biogenic and foreign sub stances of the isolated blood-perfused canine pancreas were investigated. The ma jority of cholinergic drugs such as acetylcholine, methacholine, carbachol, bethanechol pilocarpine, neostigmine, lobeline, nicotine, TMA and McN-A-343, and gastroin testinal hormones such as secretin, pancreozymin, gastrin, glucag...

Abstract Extensive research has been performed into the effectiveness of nitrification inhibitors (NIs) in preventing N losses; however, tropical agriculture underrepresented recent meta-analyses. Here, we apply a meta-analytic approach using data from 50 articles to identify impact NIs (DMPP, DCD, and DCD + NBPT) on crop yield, 2 O emissions, soil NH 4 NO 3 − concentrations, volatilization sub...

Abstract Background and aims Sorghum ( bicolor ) is able to exude allelochemicals with biological nitrification inhibition (BNI) capacity. Therefore, sorghum might be an option as cover crop since its BNI ability may reduce N pollution in the following due a decreased nitrification. However, exudation related physiological state development of plant, so abiotic stresses such drought modify rate...

Effects of various neuropharmacological agents on the motility of Dipylidium caninum was studied. 5-HT stimulated the motility of D. caninum, while other drugs such as GABA, adrenaline, phenylephrine, isoproterenol, dibenamine, and propranolol showed little effect. The stimulatory action of 5-HT was antagonized by tryptophol. Stibnal caused paralysis which was blocked by the pretreatment with 5...

Glioblastoma multiforme (GBM) are the most common primary malignant brain tumor in adults, with a median survival of about one year. This poor prognosis is attributed primarily to therapeutic resistance and tumor recurrence after surgical removal, with the root cause suggested to be found in glioblastoma stem cells (GSCs). Using glial fibrillary acidic protein (GFAP) as a reporter of astrocytic...

Melatonin secretion from the pineal gland is triggered by norepinephrine released from sympathetic terminals at night. In contrast, cholinergic and parasympathetic inputs, by activating nicotinic cholinergic receptors (nAChR), have been suggested to counterbalance the noradrenergic input. Here we investigated whether adrenergic signaling regulates nAChR channels in rat pinealocytes. Acetylcholi...